SCHEMBL3619552

SCHEMBL3619552

CC(=O)Nc1ncnc2c1[nH]c(=O)n2[C@H]1C[C@H](O)[C@@H](CO)O1

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.43
ADK P55263 1/20 0.42
TK1 P04183 2/20 0.41
LMNA P02545 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ADORA3 P0DMS8 1/20 0.41
ADORA2A P29274 1/20 0.41
TK2 O00142 1/20 0.41
SLC29A1 Q99808 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3619557 1.00 HIF1A (0.43) HIF1AADKTK1LMNASMN1; SMN2
SCHEMBL26787569 0.91 HIF1A (0.41) HIF1AADKTK1LMNASMN1; SMN2
SCHEMBL26647531 0.91 HIF1A (0.41) HIF1AADKTK1LMNASMN1; SMN2
SCHEMBL5872532 0.90 HIF1A (0.44) HIF1AADKTK1LMNASMN1; SMN2
SCHEMBL6335273 0.90 HIF1A (0.44) HIF1AADKTK1LMNASMN1; SMN2
SCHEMBL5981921 0.90 HIF1A (0.44) HIF1AADKTK1LMNASMN1; SMN2
SCHEMBL5981933 0.90 HIF1A (0.44) HIF1AADKTK1LMNASMN1; SMN2
SCHEMBL26787555 0.88 TK1 (0.45) HIF1AADKTK1LMNASMN1; SMN2
SCHEMBL26787573 0.87 HIF1A (0.42) HIF1AADKTK1LMNASMN1; SMN2
SCHEMBL23215743 0.87 ADK (0.46) ADKADORA3ADORA2ASLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3236396-A None JP disclosed
US-7851157-B1 Oligonucleotide derivative, probe for detection of gene, and DNA chip TOKYO INSTITUTE OF TECHNOLOGY (JP) 2010-12-14 US disclosed
EP-1860115-A1 OLIGONUCLEOTIDE DERIVATIVE, PROBE FOR DETECTION OF GENE, AND DNA CHIP Tokyo Institute of Technology (JP) 2007-11-28 EP disclosed
JP-H03236396-A MODIFIED OLIGODEOXYNUCLEOTIDE AND DNA CONTAINING SAME NUCLEOTIDE TOSOH CORP 1991-10-22 JP disclosed