SCHEMBL3620028

SCHEMBL3620028

C=CC(=O)Oc1ccc(OC(=O)[C@H]2CC[C@H](CCCC)CC2)cc1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
THRB P10828 4/20 0.52
KMT2A Q03164 2/20 0.45
HTT P42858 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43
F2 P00734 1/20 0.43
ELANE P08246 1/20 0.42
THRA P10827 2/20 0.40
HPGD P15428 3/20 0.39
TSHR P16473 1/20 0.39
POLB P06746 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
LSS P48449 1/20 0.38
LMNA P02545 1/20 0.38
MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3620031 1.00 THRB (0.52) THRBKMT2AHTTSMN1; SMN2TDP1
SCHEMBL3620303 0.96 THRB (0.54) THRBKMT2AHTTSMN1; SMN2TDP1
SCHEMBL3620302 0.96 THRB (0.54) THRBKMT2AHTTSMN1; SMN2TDP1
SCHEMBL3617484 0.92 THRB (0.51) THRBKMT2AHTTSMN1; SMN2TDP1
SCHEMBL3617483 0.92 THRB (0.51) THRBKMT2AHTTSMN1; SMN2TDP1
SCHEMBL14192321 0.85 THRB (0.47) THRBKMT2AHTTSMN1; SMN2TDP1
SCHEMBL7913960 0.85 HTT (0.49) KMT2AHTTSMN1; SMN2TDP1GAA
SCHEMBL7913964 0.85 HTT (0.49) KMT2AHTTSMN1; SMN2TDP1GAA
SCHEMBL8218420 0.85 SMN1; SMN2 (0.49) KMT2AHTTSMN1; SMN2TDP1GAA
SCHEMBL14401435 0.85 HTT (0.49) KMT2AHTTSMN1; SMN2TDP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7738346-B2 Polarizing diffraction element and optical head device ASAHI GLASS COMPANY, LIMITED (JP) 2010-06-15 US disclosed
US-20060239171-A1 Polarizing diffraction element and optical head device ASAHI GLASS COMPANY LIMITED (JP) 2006-10-26 US disclosed
EP-1698917-A1 POLARIZING DIFFRACTION ELEMENT AND OPTICAL HEAD DEVICE Asahi Glass Company, Limited (JP) 2006-09-06 EP disclosed