SCHEMBL3620302

SCHEMBL3620302

C=CC(=O)Oc1ccc(OC(=O)[C@H]2CC[C@H](CCCCC)CC2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 4/20 0.54
HTT P42858 2/20 0.44
KMT2A Q03164 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
F2 P00734 1/20 0.42
THRA P10827 2/20 0.41
ELANE P08246 1/20 0.41
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
PKM P14618 1/20 0.40
LSS P48449 1/20 0.39
MEN1 O00255 1/20 0.39
HPGD P15428 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
TSHR P16473 1/20 0.38
TP53 P04637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3620303 1.00 THRB (0.54) THRBHTTKMT2ASMN1; SMN2TDP1
SCHEMBL3620031 0.96 THRB (0.52) THRBHTTKMT2ASMN1; SMN2TDP1
SCHEMBL3620028 0.96 THRB (0.52) THRBHTTKMT2ASMN1; SMN2TDP1
SCHEMBL3617483 0.91 THRB (0.51) THRBHTTKMT2ASMN1; SMN2TDP1
SCHEMBL3617484 0.91 THRB (0.51) THRBHTTKMT2ASMN1; SMN2TDP1
SCHEMBL14192321 0.89 THRB (0.47) THRBHTTKMT2ASMN1; SMN2TDP1
SCHEMBL12154179 0.87 THRB (0.47) THRBHTTKMT2ASMN1; SMN2TDP1
SCHEMBL3361040 0.87 THRB (0.53) THRBHTTKMT2ATHRAGAA
SCHEMBL9458110 0.87 SMN1; SMN2 (0.41) THRBHTTKMT2ASMN1; SMN2TDP1
SCHEMBL9458101 0.87 SMN1; SMN2 (0.41) THRBHTTKMT2ASMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7738346-B2 Polarizing diffraction element and optical head device ASAHI GLASS COMPANY, LIMITED (JP) 2010-06-15 US disclosed
US-20060239171-A1 Polarizing diffraction element and optical head device ASAHI GLASS COMPANY LIMITED (JP) 2006-10-26 US disclosed
EP-1698917-A1 POLARIZING DIFFRACTION ELEMENT AND OPTICAL HEAD DEVICE Asahi Glass Company, Limited (JP) 2006-09-06 EP disclosed
US-6562259-B1 Photopolymerizable liquid crystal monomer is a 4-(4-(alkyloxycarbonyloxy)benzoyloxy)phenyl acrylate; optical head employing the optical element as a polarizing hologram element ASAHI GLASS COMPANY, LIMITED (JP) 2003-05-13 US disclosed