Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.57 |
| ▸ | ABL1 | P00519 | 2/20 | 0.57 |
| ▸ | BCR | P11274 | 2/20 | 0.57 |
| ▸ | PRKCA | P17252 | 2/20 | 0.57 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.57 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.57 |
| ▸ | SRC | P12931 | 1/20 | 0.57 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.57 |
| ▸ | PRKACA | P17612 | 1/20 | 0.57 |
| ▸ | PRKACG | P22612 | 1/20 | 0.57 |
| ▸ | PRKACB | P22694 | 1/20 | 0.57 |
| ▸ | GSK3B | P49841 | 2/20 | 0.48 |
| ▸ | CDK2 | P24941 | 4/20 | 0.46 |
| ▸ | CAMK2D | Q13557 | 4/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.46 |
| ▸ | CDK4 | P11802 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3621350 | 0.94 | ABL1 (0.54) | EGFRABL1BCRPRKCAPRKCD | |
| SCHEMBL3611979 | 0.90 | ABL1 (0.58) | EGFRABL1BCRPRKCAPRKCD | |
| SCHEMBL3607076 | 0.89 | ABL1 (0.70) | EGFRABL1BCRPRKCAPRKCD | |
| SCHEMBL3615744 | 0.89 | ABL1 (0.58) | EGFRABL1BCRPRKCAPRKCD | |
| SCHEMBL3620948 | 0.88 | EGFR (0.56) | EGFRABL1BCRPRKCAPRKCD | |
| SCHEMBL3613177 | 0.87 | ABL1 (0.62) | EGFRABL1BCRPRKCAPRKCD | |
| SCHEMBL3619252 | 0.87 | ABL1 (0.56) | EGFRABL1BCRPRKCAPRKCD | |
| SCHEMBL3615039 | 0.86 | ABL1 (0.55) | EGFRABL1BCRPRKCAPRKCD | |
| SCHEMBL3625448 | 0.86 | EGFR (0.57) | EGFRABL1BCRPRKCAPRKCD | |
| SCHEMBL3615802 | 0.84 | EGFR (0.56) | EGFRABL1BCRPRKCAPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100093776-A1 | Organic Compounds and Their Uses | NOVARTIS AG | 2010-04-15 | — | — | US | disclosed |
| US-20100093776-A1 | Organic Compounds and Their Uses | NOVARTIS AG | 2010-04-15 | — | — | US | disclosed |
| US-20100093776-A1 | Organic Compounds and Their Uses | NOVARTIS AG | 2010-04-15 | — | — | US | disclosed |
| WO-2008079918-A1 | INDOL-4-YL-PYRIMIDINYL-2-YL-AMINE DERIVATIVES AND USE THEREOF AS CYCLIN DEPENDANT KINASE INHIBITORS | NOVARTIS AG (CH) | 2008-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093776-A1 | Organic Compounds and Their Uses | OAT, OTC, AOX1 | EGFR 4114/4885ABL1 3215/4885BCR 3115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.