Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.41 |
| ▸ | CDK2 | P24941 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CDK4 | P11802 | 2/20 | 0.41 |
| ▸ | CCND1 | P24385 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30200294 | 1.00 | MAPT (0.43) | MAPTGAAALDH1A1RAB9AKDM4E | |
| Biphenyl SCHEMBL27928291 | 0.93 | GAA (0.42) | MAPTGAAALDH1A1RAB9AKDM4E | |
| SCHEMBL30562839 | 0.84 | KDM4E (0.39) | MAPTGAAALDH1A1RAB9AKDM4E | |
| SCHEMBL19032530 | 0.82 | KDM4E (0.38) | MAPTGAAALDH1A1RAB9AKDM4E | |
| SCHEMBL10704355 | 0.81 | KDM4E (0.43) | MAPTALDH1A1KDM4EGPR3EGFR | |
| SCHEMBL10707622 | 0.81 | KDM4E (0.43) | MAPTALDH1A1KDM4EGPR3EGFR | |
| SCHEMBL322264 | 0.79 | CYP1A2 (0.42) | MAPTALDH1A1KDM4EGPR3EGFR | |
| SCHEMBL31391354 | 0.76 | ALDH1A1 (0.43) | MAPTGAAALDH1A1RAB9AKDM4E | |
| SCHEMBL30071208 | 0.76 | MALT1 (0.49) | MAPTGAAALDH1A1RAB9AKDM4E | |
| SCHEMBL30368951 | 0.76 | CYP1A2 (0.40) | MAPTGAAALDH1A1KDM4EGPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106414430-A | Pharmacologically active quinazolinedione derivatives | 奥赖恩公司 | 2017-02-15 | — | — | CN | claimed |
| CN-103910688-A | 2-propyl-4-chloroquinazoline derivative, its preparation method thereof and its application thereof | CHUNLIN CHEN | 2014-07-09 | — | — | CN | claimed |
| CN-101679311-A | Quinazoline compound | WYETH CORP | 2010-03-24 | — | — | CN | claimed |
| EP-2142517-A2 | QUINAZOLINE COMPOUNDS | Wyeth (US) | 2010-01-13 | — | — | EP | claimed |
| WO-2009020683-A2 | QUINAZOLINE COMPOUNDS | WYETH (US) | 2009-02-12 | — | — | WO | claimed |
| WO-2025022007-A1 | PESTICIDALLY ACTIVE QUINAZOLINE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2025-01-30 | — | — | WO | disclosed |
| CN-117561252-A | 2- [3- [1[ (quinazolin-4-yl) amino ] ethyl ] pyrazin-2-yl ] thiazole-5-carbonitrile derivatives and similar compounds as pesticides | 先正达农作物保护股份公司 | 2024-02-13 | — | — | CN | disclosed |
| WO-2024030647-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF RAS | THERAS, INC. (US) | 2024-02-08 | — | — | WO | disclosed |
| US-20240032541-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2024-02-01 | — | — | US | disclosed |
| WO-2024008179-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BEIGENE, LTD. (KY) | 2024-01-11 | — | — | WO | disclosed |
| CN-114436975-B | 2-trifluoromethyl-4-aminoquinazoline compound and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-10-31 | — | — | CN | disclosed |
| WO-2023179703-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BEIGENE , LTD. (KY) | 2023-09-28 | — | — | WO | disclosed |
| EP-0545491-B1 | Photographic silver halide colour materials | KODAK LTD (GB) | 1998-10-14 | — | — | EP | disclosed |
| EP-0565165-B1 | Photographic silver halide colour materials | KODAK LTD (GB) | 1998-09-02 | — | — | EP | disclosed |
| EP-0760819-A1 | TRICYCLIC DICARBONYL DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1997-03-12 | — | — | EP | disclosed |
| WO-1995032205-A1 | TRICYCLIC DICARBONYL DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1995-11-30 | — | — | WO | disclosed |
| US-5415981-A | Sulfohydrazide developer, heteroarylacetonitrile color coupler | EASTMAN KODAK COMPANY (US) | 1995-05-16 | — | — | US | disclosed |
| US-5284739-A | Devloper and coupler present in drops of a high-boiling solvent; water pollution control | EASTMAN KODAK COMPANY (US) | 1994-02-08 | — | — | US | disclosed |
| EP-0565165-A1 | Photographic silver halide colour materials | KODAK LIMITED (GB) | 1993-10-13 | — | — | EP | disclosed |
| EP-0545491-A1 | Photographic silver halide colour materials | KODAK LIMITED (GB) | 1993-06-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240032541-A1 | HERBICIDAL COMPOUNDS | HAX1, DDT, MTX1 | MAPT 4243/4885GAA 604/4885ALDH1A1 264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.