Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL572694 | 0.81 | TSHR (0.33) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL6293184 | 0.78 | POLB (0.33) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL27740034 | 0.74 | TSHR (0.41) | TSHRALDH1A1 | |
| SCHEMBL19386097 | 0.72 | TDP1 (0.43) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| Phosphoric Acid SCHEMBL8763248 | 0.72 | TSHR (0.49) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL27565567 | 0.72 | TSHR (0.38) | TSHRALDH1A1 | |
| SCHEMBL9276375 | 0.71 | ALDH1A1 (0.48) | TSHRALDH1A1 | |
| SCHEMBL29068293 | 0.70 | THRB (0.36) | TSHRALDH1A1 | |
| Phosphoric Acid SCHEMBL8763237 | 0.70 | TSHR (0.50) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL819118 | 0.70 | CHRM5 (0.40) | TSHRCHRM2CHRM4CHRM1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1669093-B1 | Polyoxyalkylene copolymer blends as biomaterial for drug delivery and surface modification | TYCO HEALTHCARE (US) | 2010-02-24 | — | — | EP | claimed |