SCHEMBL3624258

SCHEMBL3624258

CCCCCCCCC(C)(C)S

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.47
THRB P10828 1/20 0.47
GGPS1 O95749 6/20 0.41
FDPS P14324 9/20 0.39
SMPD1 P17405 2/20 0.38
CES2 O00748 1/20 0.38
LPAR1 Q92633 1/20 0.38
LPAR3 Q9UBY5 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3608808 1.00 TSHR (0.47) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL50029 1.00 TSHR (0.47) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL51185 1.00 TSHR (0.47) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL971499 1.00 TSHR (0.47) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL3624293 1.00 TSHR (0.47) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL10931906 1.00 TSHR (0.47) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL23034285 1.00 TSHR (0.47) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL3625459 1.00 TSHR (0.47) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL8622066 1.00 TSHR (0.47) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL21128 1.00 TSHR (0.47) TSHRTHRBGGPS1FDPSSMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4279527-A1 BIODEGRADABLE POLYESTER RESIN COMPOSITION Ecovance Co. Ltd (KR) 2023-11-22 EP disclosed
EP-3140308-B1 PROCESS FOR THE PREPARATION OF OPIOID COMPOUNDS NORAMCO LLC (US) 2023-05-24 EP disclosed
US-9701687-B2 Process for the preparation of opioid compounds NORAMCO, INC. (US) 2017-07-11 US disclosed
US-9701688-B2 Process for the preparation of opioid compounds NORAMCO, INC. (US) 2017-07-11 US disclosed
EP-3140307-A2 PROCESS FOR THE PREPARATION OF OPIOID COMPOUNDS Noramco, Inc. (US) 2017-03-15 EP disclosed
EP-3140308-A2 PROCESS FOR THE PREPARATION OF OPIOID COMPOUNDS Noramco, Inc. (US) 2017-03-15 EP disclosed
WO-2015171354-A2 PROCESS FOR THE PREPARATION OF OPIOID COMPOUNDS NORAMCO, INC. (US) 2015-11-12 WO disclosed
WO-2015171353-A2 PROCESS FOR THE PREPARATION OF OPIOID COMPOUNDS NORAMCO, INC. (US) 2015-11-12 WO disclosed
US-20150315204-A1 PROCESS FOR THE PREPARATION OF OPIOID COMPOUNDS NORAMCO, LLC (FORMERLY KNOWN AS NORAMCO, INC.) 2015-11-05 US disclosed
US-20150315205-A1 PROCESS FOR THE PREPARATION OF OPIOID COMPOUNDS NORAMCO, LLC (FORMERLY KNOWN AS NORAMCO, INC.) 2015-11-05 US disclosed
US-5705085-A DURABILITY, REDUCED THICKENING; BRAKES, CLUTCHES LORD CORPORATION (US) 1998-01-06 US disclosed
WO-1997048110-A1 MAGNETORHEOLOGICAL FLUID LORD CORPORATION (US) 1997-12-18 WO disclosed
WO-1997048109-A1 ORGANOMOLYBDENUM-CONTAINING MAGNETORHEOLOGICAL FLUID LORD CORPORATION (US) 1997-12-18 WO disclosed
US-5683615-A Magnetorheological fluid LORD CORPORATION (US) 1997-11-04 US disclosed
EP-0276497-B1 PROCESS FOR THE PRODUCTION OF MULTIPLE RADIOGRAPHIC IMAGES AGFA-GEVAERT N.V. (BE) 1991-10-09 EP disclosed
US-4893021-A Exposure of multiple photosensitive layers; of fluorescent material and visible light reflectors AGFA-GEVAERT, N.V. (BE) 1990-01-09 US disclosed
EP-0276497-A1 Process for the production of multiple radiographic images AGFA-GEVAERT N.V. (BE) 1988-08-03 EP disclosed
US-4177071-A HIGH SENSITIVITY TO PENTRATING RADIATION; INSENSITIVE TO FORMATION OF PRESSURE MARKS AGFA-GEVAERT, N.V. (BE) 1979-12-04 US disclosed
US-4130429-A X*RAY FLUORESCENT SCREEN, SILVER HALIDE AGFA-GEVAERT, N.V. (BE) 1978-12-19 US disclosed
US-4130428-A FLUORESCENT SCREEN AGFA-GEVAERT, N.V. (BE) 1978-12-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150315205-A1 PROCESS FOR THE PREPARATION OF OPIOID COMPOUNDS OPRK1, OPRL1, OPRM1 TSHR 3669/4885THRB 553/4885GGPS1 4366/4885
US-20150315204-A1 PROCESS FOR THE PREPARATION OF OPIOID COMPOUNDS OPRK1, OPRL1, OPRM1 TSHR 3669/4885THRB 553/4885GGPS1 4366/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.