Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9821204 | 0.80 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2FFAR3CETP | |
| SCHEMBL6866082 | 0.75 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2FFAR3CETP | |
| SCHEMBL12626878 | 0.75 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2FFAR3CETP | |
| SCHEMBL12660610 | 0.75 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2FFAR3CETP | |
| SCHEMBL6682954 | 0.75 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL14407687 | 0.75 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2FFAR3CETP | |
| SCHEMBL11843545 | 0.75 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL17574280 | 0.75 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2FFAR3CETP | |
| SCHEMBL19189160 | 0.75 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL17727988 | 0.74 | HSD11B1 (0.37) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2178373-A1 | HETEROCYCLES AS POTASSIUM CHANNEL MODULATORS | Icagen, Inc. (US) | 2010-04-28 | — | — | EP | claimed |
| WO-2009026254-A1 | HETEROCYCLES AS POTASSIUM CHANNEL MODULATORS | ICAGEN, INC. (US) | 2009-02-26 | — | — | WO | claimed |