SCHEMBL3624714

SCHEMBL3624714

CC1=CC(=O)C(=O)C=C1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.50
▸ MAPT P10636 5/20 0.50
▸ MEN1 O00255 3/20 0.50
▸ MAPK1 P28482 3/20 0.50
▸ BLM P54132 3/20 0.50
▸ KMT2A Q03164 3/20 0.50
▸ LMNA P02545 3/20 0.50
▸ USP2 O75604 2/20 0.50
▸ GAA P10253 2/20 0.50
▸ TP53 P04637 2/20 0.50
▸ CYP1A2 P05177 2/20 0.50
▸ CYP3A4 P08684 2/20 0.50
▸ HSPD1 P10809 2/20 0.50
▸ HPGD P15428 2/20 0.50
▸ CDC25A P30304 2/20 0.50
▸ CDC25B P30305 2/20 0.50
▸ HSPE1 P61604 2/20 0.50
▸ SMN1; SMN2 Q16637 2/20 0.50
▸ TST Q16762 2/20 0.50
▸ IDO1 P14902 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
P-Xyloquinone SCHEMBL49964 0.83 PLK1 (0.60) ALDH1A1MAPTMEN1MAPK1BLM
SCHEMBL17581103 0.77 — —
SCHEMBL22805 0.77 MAPT (0.46) ALDH1A1MAPTMEN1MAPK1BLM
SCHEMBL7897027 0.77 ALDH1A1 (0.41) ALDH1A1MAPTMEN1MAPK1BLM
SCHEMBL14507720 0.75 ALDH1A1 (0.44) ALDH1A1MAPTMEN1MAPK1BLM
SCHEMBL11025815 0.73 MAPT (0.50) ALDH1A1MAPTMEN1MAPK1BLM
SCHEMBL14507718 0.72 PLK1 (0.50) ALDH1A1MAPTMEN1MAPK1BLM
SCHEMBL2137325 0.71 ALDH1A1 (0.48) ALDH1A1MAPTMEN1MAPK1BLM
SCHEMBL755506 0.71 ALDH1A1 (0.48) ALDH1A1MAPTMEN1MAPK1BLM
SCHEMBL9653457 0.71 MAPT (0.41) ALDH1A1MAPTMEN1MAPK1BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0460996-B1 Keratinic fibres dyeing process with an aminoindol associated with a quinone derivative OREAL (FR) 1994-09-14 — — EP claimed
US-5180400-A METHOD FOR DYEING KERATINOUS FIBRES USING AN AMINOINDOLE IN COMBINATION WITH A QUINONE DERIVATIVE L'OREAL (FR) 1993-01-19 — — US claimed
EP-0460996-A1 Keratinic fibres dyeing process with an aminoindol associated with a quinone derivative L'OREAL (FR) 1991-12-11 — — EP claimed
EP-0376776-A2 Process for dyeing keratinous fibres with hydroxyindole associated with quinone and 1,4-benzoquinone L'OREAL (FR) 1990-07-04 — — EP claimed
US-20220175954-A1 HYPOXIA-INDUCING CRYOGELS NORTHEASTERN UNIVERSITY 2022-06-09 — — US disclosed
US-20180159141-A1 Non-Platinum Group Oxygen Reduction Reaction Catalysts BATTELLE SAVANNAH RIVER ALLIANCE, LLC 2018-06-07 — — US disclosed
US-20180159141-A1 Non-Platinum Group Oxygen Reduction Reaction Catalysts BATTELLE SAVANNAH RIVER ALLIANCE, LLC 2018-06-07 — — US disclosed
WO-2010134580-A1 METHOD FOR PRODUCING AROMATIC FLUORINE COMPOUND AND NOVEL COMPOUND 静岡県公立大学法人 (JP) 2010-11-25 — — WO disclosed
WO-2010134580-A1 METHOD FOR PRODUCING AROMATIC FLUORINE COMPOUND AND NOVEL COMPOUND 静岡県公立大学法人 (JP) 2010-11-25 — — WO disclosed
EP-1457813-B1 An improved electrochromic medium capable of producing a pre-selected color GENTEX CORP (US) 2007-01-24 — — EP disclosed
EP-1457813-A2 An improved electrochromic medium capable of producing a pre-selected color Gentex Corporation (US) 2004-09-15 — — EP disclosed
EP-0972227-B1 AN IMPROVED ELECTROCHROMIC MEDIUM CAPABLE OF PRODUCING A PRE-SELECTED COLOR GENTEX CORP (US) 2004-07-14 — — EP disclosed
EP-0460996-B1 Keratinic fibres dyeing process with an aminoindol associated with a quinone derivative OREAL (FR) 1994-09-14 — — EP disclosed
EP-0603322-A1 DYEING COMPOSITION BASED ON HYDROXYINDOLINE DERIVATIVES. OREAL (FR) 1994-06-29 — — EP disclosed
WO-1993005018-A1 DYEING COMPOSITION BASED ON HYDROXYINDOLINE DERIVATIVES L'OREAL (FR) 1993-03-18 — — WO disclosed
US-5180400-A METHOD FOR DYEING KERATINOUS FIBRES USING AN AMINOINDOLE IN COMBINATION WITH A QUINONE DERIVATIVE L'OREAL (FR) 1993-01-19 — — US disclosed
EP-0376776-B1 PROCESS FOR DYEING KERATINOUS FIBRES WITH HYDROXYINDOLE ASSOCIATED WITH QUINONE AND 1,4-BENZOQUINONE L'OREAL (FR) 1992-09-23 — — EP disclosed
EP-0460996-A1 Keratinic fibres dyeing process with an aminoindol associated with a quinone derivative L'OREAL (FR) 1991-12-11 — — EP disclosed
US-5053053-A PROCESS FOR DYEING KERATINOUS FIBRES WITH A HYDROXYINDOLE IN COMBINATION WITH A QUINONE DERIVATIVE; AND NOVEL 1,4-BENZOQUINONES L'OREAL (FR) 1991-10-01 — — US disclosed
EP-0376776-A2 Process for dyeing keratinous fibres with hydroxyindole associated with quinone and 1,4-benzoquinone L'OREAL (FR) 1990-07-04 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220175954-A1 HYPOXIA-INDUCING CRYOGELS HIF1A, HYOU1, HIF1AN ALDH1A1 2762/4885MAPT 3758/4885MEN1 4740/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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