SCHEMBL3625705

SCHEMBL3625705

C=Cc1ccc(CC(=O)Cl)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
TDP1 Q9NUW8 1/20 0.41
LMNA P02545 2/20 0.39
PSMD14 O00487 1/20 0.39
TAS1R3 Q7RTX0 2/20 0.37
TAS1R1 Q7RTX1 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
TSHR P16473 1/20 0.36
POLB P06746 1/20 0.36
TP53 P04637 3/20 0.35
MAPT P10636 3/20 0.35
CA2 P00918 2/20 0.34
CAMK2A Q9UQM7 1/20 0.34
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
CTSC P53634 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA7 P36544 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9680264 0.83 ALDH1A1 (0.50) ALDH1A1TDP1LMNAPSMD14TAS1R3
SCHEMBL4194796 0.82 CA2 (0.46) ALDH1A1LMNATSHRCA2CAMK2A
SCHEMBL598224 0.81 CA2 (0.56) ALDH1A1TDP1LMNATSHRPOLB
SCHEMBL3816810 0.80 ALDH1A1 (0.42) ALDH1A1TDP1LMNAPSMD14TAS1R3
SCHEMBL3623872 0.80 BCHE (0.42) ALDH1A1TDP1LMNAPSMD14TAS1R3
SCHEMBL10591543 0.79 POLB (0.47) ALDH1A1TDP1LMNAPSMD14TAS1R3
SCHEMBL4456785 0.79 CA2 (0.57) ALDH1A1TDP1LMNACA2
SCHEMBL10882377 0.79 CYP1A2 (0.49) ALDH1A1TDP1SMN1; SMN2TSHRPOLB
SCHEMBL10804149 0.79 CA2 (0.34) ALDH1A1LMNATSHRPOLBMAPT
SCHEMBL29109718 0.79 ALDH1A1 (0.46) ALDH1A1TDP1LMNAPSMD14TAS1R3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1537876-B Multi-branch polymer, its production method and its application MITSU CHEMICALS INC 2013-01-16 CN disclosed
US-7795347-B2 Multi-branched polymer, process for producing the same, and applications thereof MITSUI CHEMICALS, INC. (JP) 2010-09-14 US disclosed
EP-1396504-B1 Polyolefin macromonomer, graft polymer obtained from the polyolefin macromonomer, and use thereof MITSUI CHEMICALS INC (JP) 2009-01-14 EP disclosed
EP-1457512-B1 Multi-branched polymer, process for producing the same, and applications thereof MITSUI CHEMICALS INC (JP) 2008-05-07 EP disclosed
CN-1276935-C Polyolefine macromonomer, graftmer obtained by utilizing polyolefine macromonomer and its application MITSUI CHEMICALS INC (JP) 2006-09-27 CN disclosed
US-7067587-B2 Polyolefin macromonomer, graft polymer obtained from the polyolefin macromonomer, and use thereof MITSUI CHEMICALS, INC. (JP) 2006-06-27 US disclosed
US-20040242791-A1 Polyolefin macromonomer, graft polymer obtained from the polyolefin macromonomer, and use thereof MITSUI CHEMICALS, INC. (JP) 2004-12-02 US disclosed
US-20040220346-A1 Multi-branched polymer, process for producing the same, and applications thereof MITSUI CHEMICALS, INC. (JP) 2004-11-04 US disclosed
CN-1537876-A Multi-branch polymer, its production method and its application ������ѧ��ʽ���� 2004-10-20 CN disclosed
EP-1457512-A1 Multi-branched polymer, process for producing the same, and applications thereof Mitsui Chemicals, Inc. (JP) 2004-09-15 EP disclosed
CN-1495209-A Polyolefine macromonomer, graftmer obtained by utilizing polyolefine macromonomer and its application ������ѧ��ʽ���� 2004-05-12 CN disclosed
EP-1396504-A2 Polyolefin macromonomer, graft polymer obtained from the polyolefin macromonomer, and use thereof Mitsui Chemicals, Inc. (JP) 2004-03-10 EP disclosed
US-4008276-A ANTIINFLAMMATORY STERLING DRUG INC. (US) 1977-02-15 US disclosed
US-3965105-A ANTIINFLAMMATORY STERLING DRUG INC. (US) 1976-06-22 US disclosed