Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 3/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2344340 | 1.00 | PREP (0.46) | PREPALDH1A1GAACASP3CASP1 | |
| SCHEMBL2344349 | 1.00 | PREP (0.46) | PREPALDH1A1GAACASP3CASP1 | |
| SCHEMBL3736228 | 0.91 | CPB1 (0.50) | PREPALDH1A1GAACASP3CASP1 | |
| SCHEMBL3736224 | 0.91 | CPB1 (0.50) | PREPALDH1A1GAACASP3CASP1 | |
| SCHEMBL3736230 | 0.91 | CPB1 (0.50) | PREPALDH1A1GAACASP3CASP1 | |
| SCHEMBL13411397 | 0.89 | PREP (0.43) | PREPGAACASP3CASP1CTSK | |
| SCHEMBL1841237 | 0.89 | PREP (0.43) | PREPGAACASP3CASP1CTSK | |
| SCHEMBL13446212 | 0.88 | CASP3 (0.45) | PREPALDH1A1GAACASP3CASP1 | |
| SCHEMBL14313605 | 0.87 | CASP3 (0.50) | PREPALDH1A1GAACASP3CASP1 | |
| SCHEMBL3250376 | 0.87 | CASP3 (0.47) | PREPALDH1A1GAACASP3CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2184283-A1 | Process for preparing compounds useful as intermediates for the preparation of modulators of chemokine receptor activity | Bristol-Myers Squibb Company (US) | 2010-05-12 | — | — | EP | disclosed |