Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31507714 | 0.87 | ADORA2A (0.43) | KDM4EADORA2AADORA1LMNAALDH1A1 | |
| SCHEMBL9676504 | 0.79 | SMN1; SMN2 (0.47) | MAPTKDM4EADORA2AADORA1LMNA | |
| SCHEMBL558692 | 0.73 | PIM1 (0.38) | MAPTCYP2D6CYP1A2KDM4EKMT2A | |
| SCHEMBL20416864 | 0.72 | KDM4E (0.46) | MAPTCYP2D6CYP1A2KDM4EKMT2A | |
| SCHEMBL16505415 | 0.72 | KDM4E (0.44) | MAPTCYP2D6CYP1A2KDM4EALDH1A1 | |
| SCHEMBL2848707 | 0.69 | KDM4E (0.43) | MAPTCYP1A2KDM4EKMT2ALMNA | |
| SCHEMBL29875720 | 0.69 | CYP1A2 (0.45) | MAPTCYP2D6CYP1A2KDM4EKMT2A | |
| SCHEMBL3652790 | 0.68 | ADORA2A (0.36) | MAPTCYP2D6CYP1A2KDM4EADORA2A | |
| SCHEMBL24253899 | 0.68 | CYP2D6 (0.41) | MAPTCYP2D6CYP1A2KDM4EKMT2A | |
| SCHEMBL140640 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010119878-A1 | PYRIMIDINE COMPOUND AND ITS USE FOR PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-10-21 | — | — | WO | disclosed |
| WO-2010119878-A1 | PYRIMIDINE COMPOUND AND ITS USE FOR PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-10-21 | — | — | WO | disclosed |