Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 12/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20416864 | 0.76 | KDM4E (0.46) | CYP1A2CYP2D6MAPTNOTUMKMT2A | |
| SCHEMBL10691665 | 0.72 | NOTUM (0.66) | CYP1A2NOTUM | |
| SCHEMBL29876396 | 0.69 | ADORA2A (0.44) | MAPTKDM4E | |
| SCHEMBL20242767 | 0.69 | NOTUM (0.41) | NOTUMMAP3K5 | |
| SCHEMBL3625872 | 0.69 | MAPT (0.45) | CYP1A2CYP2D6MAPTKMT2ALMNA | |
| SCHEMBL3510845 | 0.68 | NOTUM (0.50) | CYP1A2CYP2D6NOTUMKMT2AMAP3K5 | |
| SCHEMBL140640 | 0.67 | — | — | |
| SCHEMBL19814823 | 0.66 | NOTUM (0.52) | CYP1A2NOTUM | |
| SCHEMBL23931283 | 0.66 | MAPT (0.62) | CYP1A2CYP2D6MAPTKMT2ALMNA | |
| SCHEMBL1318180 | 0.66 | MAPT (0.72) | CYP1A2CYP2D6MAPTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022203267-A1 | DUAL ANTAGONIST FOR ADENOSINE A2A RECEPTOR AND ADENOSINE A2B RECEPTOR AND USE THEREOF | 주식회사 스탠다임 | 2022-09-29 | — | — | WO | disclosed |