Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tetrahydrofuran. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrofuran SCHEMBL3852066 | 1.00 | ALDH1A1 (0.73) | — | |
| Tetrahydrofuran SCHEMBL21496006 | 0.95 | — | — | |
| Tetrahydrofuran SCHEMBL27262153 | 0.95 | — | — | |
| Tetrahydrofuran SCHEMBL25278588 | 0.91 | — | — | |
| Tetrahydrofuran SCHEMBL11793203 | 0.91 | — | — | |
| Tetrahydrofuran SCHEMBL27261909 | 0.91 | — | — | |
| Tetrahydrofuran SCHEMBL2219545 | 0.86 | — | — | |
| Tetrahydrofuran SCHEMBL1278401 | 0.86 | — | — | |
| Tetrahydrofuran SCHEMBL15821488 | 0.86 | — | — | |
| Tetrahydrofuran SCHEMBL2177525 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 254 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117362622-A | Method and device for improving end of perfluoropolyether | 上海贯新科技有限公司 | 2024-01-09 | — | — | CN | claimed |
| CN-114907836-B | Multistage light response type fluorescent liquid crystal element, polymer thereof and preparation method thereof | 西北工业大学 | 2023-10-27 | — | — | CN | claimed |
| CN-113862000-B | Fluorescent color continuously adjustable liquid crystal polymer and preparation method thereof | 西北工业大学 | 2023-07-11 | — | — | CN | claimed |
| CN-116332168-A | Preparation method and application of graphene-carbon nanotube composite material | 重庆中润新材料股份有限公司 | 2023-06-27 | — | — | CN | claimed |
| CN-114907836-A | Multistage photoresponse type fluorescent liquid crystal element, polymer thereof and preparation method thereof | 西北工业大学 | 2022-08-16 | — | — | CN | claimed |
| CN-114702431-A | Preparation method of 6, 6-dimethyl-3-azabicyclo [3.1.0] hexane | 浙江江北药业有限公司 | 2022-07-05 | — | — | CN | claimed |
| CN-113862000-A | Liquid crystal polymer with continuously adjustable fluorescence color and preparation method thereof | 西北工业大学 | 2021-12-31 | — | — | CN | claimed |
| CN-106967416-B | The preparation method of titanium dioxide nano-particle fluorescence probe for DDT detection | 合肥学院 | 2019-07-02 | — | — | CN | claimed |
| CN-107863513-A | A kind of closed cage structure Si-C composite material and preparation method thereof | 中国科学院过程工程研究所 | 2018-03-30 | — | — | CN | claimed |
| CN-104086470-A | Positron nuclide labeled selenocysteine compound and application thereof | GUANGZHOU HTA ISOTOPE MEDICAL CO LTD | 2014-10-08 | — | — | CN | claimed |
| CN-102060855-B | Method for preparing octahydro-pyrro-[3,4-c] pyridine-derivatives | SHANGHAI PHARMATECH CO LTD | 2014-04-16 | — | — | CN | claimed |
| CN-102060855-A | Method for preparing octahydro-pyrro-[3,4-c] pyridine-derivatives | SHANGHAI PHARMA TECHS CO LTD | 2011-05-18 | — | — | CN | claimed |
| CN-101768115-A | Preparation method of N-[11C] methyl-N-(1-methyl propyl)-1-(2-chlorphenyl) isoquinoline-3-carbamoyl | MINGFANG WANG | 2010-07-07 | — | — | CN | claimed |
| EP-1990333-A1 | Process for the preparation of cinacalcet hydrochloride | Sandoz AG (CH) | 2008-11-12 | — | — | EP | claimed |
| EP-0973724-B1 | NOVEL PROCESS FOR THE PREPARATION OF (+/-)3- (3,4-DICHLOROPHENYL)-2- DIMETHYLAMINO-2-METHYLPROPAN-1-OL OR CERICLAMINE (INN) | PARKE DAVIS (FR) | 2003-10-01 | — | — | EP | claimed |
| US-6121491-A | Process for the preparation of (+/-)3-(3,4-dichlorophenyl)-2-dimethylamino-2-methylpropan-1-OL or cericlamine (INN) | WARNER-LAMBERT COMPANY (US) | 2000-09-19 | — | — | US | claimed |
| EP-0973724-A1 | NOVEL PROCESS FOR THE PREPARATION OF (+/-)3- (3,4-DICHLOROPHENYL)-2- DIMETHYLAMINO-2-METHYLPROPAN-1-OL OR CERICLAMINE (INN) | PARKE-DAVIS (FR) | 2000-01-26 | — | — | EP | claimed |
| WO-1998045248-A1 | NOVEL PROCESS FOR THE PREPARATION OF (+/-)3- (3,4-DICHLOROPHENYL)-2- DIMETHYLAMINO-2-METHYLPROPAN-1-OL OR CERICLAMINE (INN) | JOUVEINAL (FR) | 1998-10-15 | — | — | WO | claimed |
| WO-2024151112-A1 | PYRAZOLOPYRIMIDINE DERIVATIVE AS CYCLIN-DEPENDENT KINASE 9 INHIBITOR | 주식회사 티움바이오 | 2024-07-18 | — | — | WO | disclosed |
| US-3961053-A | STEROIDS, CONTROLLING FERTILITY AND ESTRUS | SANDOZ, INC. (US) | 1976-06-01 | — | — | US | disclosed |