⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28491812 | 0.93 | LMNA (0.53) | — | |
| SCHEMBL28988373 | 0.90 | LMNA (0.50) | — | |
| SCHEMBL6165852 | 0.90 | LMNA (0.50) | — | |
| Alcohol SCHEMBL14150364 | 0.89 | LMNA (0.43) | — | |
| Ether SCHEMBL1582237 | 0.84 | LMNA (0.40) | — | |
| SCHEMBL42290 | 0.82 | — | — | |
| SCHEMBL2566012 | 0.82 | — | — | |
| SCHEMBL16469538 | 0.82 | — | — | |
| SCHEMBL9634213 | 0.80 | — | — | |
| SCHEMBL28497585 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109134716-B | Vanadium catalyst and method for preparing olefin polymer | 北京引发科技有限公司 | 2020-11-10 | — | — | CN | claimed |
| CN-109134716-B | Vanadium catalyst and method for preparing olefin polymer | 北京引发科技有限公司 | 2020-11-10 | — | — | CN | disclosed |
| EP-2532664-A1 | Substituted indolo [2,3-a] quinolizines in the treatment of cancer | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2012-12-12 | — | — | EP | disclosed |
| EP-2046741-B1 | INDOLES AS 5-HT6 MODULATORS | PROXIMAGEN LTD (GB) | 2012-10-31 | — | — | EP | disclosed |
| US-7812017-B2 | 4-substituted indole and indoline compounds | BIOVITRUM AB (PUBL.) (SE) | 2010-10-12 | — | — | US | disclosed |
| US-20090143354-A1 | P2X7 Receptor Antagonists and Their Use | ASTRAZENECA AB (SE) | 2009-06-04 | — | — | US | disclosed |
| US-20080261977-A1 | Pyrimidine Derivatives as Cannabinoid Receptor Modulators | GLAXO GROUP LIMITED (GB) | 2008-10-23 | — | — | US | disclosed |
| US-7439240-B2 | Purine-or pyrrolol[2,3-d]pyrimidine-2-carbonitiles for treating diseases associated with cysteine protease activity | ASTRAZENECA AB (SE) | 2008-10-21 | — | — | US | disclosed |
| EP-1328515-B1 | INDOLINE DERIVATIVES AND THEIR USE AS 5-HT2 RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2008-08-06 | — | — | EP | disclosed |
| US-7408065-B2 | P2X7 receptor antagonists and their use | ASTRAZENECA AB (SE) | 2008-08-05 | — | — | US | disclosed |
| EP-1196783-A2 | SCREENING FOR THERAPEUTIC AGENTS BEING SCAP ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2002-04-17 | — | — | EP | disclosed |
| US-6342601-B1 | TREATING ALLOGRAFT REJECTION, RHEUMATOID ARTHRITIS | ASTRAZENECA AB (SE) | 2002-01-29 | — | — | US | disclosed |
| US-6300352-B1 | FOR THERAPY OF ASTHMA | ASTRAZENECA AB (SE) | 2001-10-09 | — | — | US | disclosed |
| WO-2001012603-A1 | INDOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR MEDICINAL APPLICATION | VERNALIS RESEARCH LIMITED (GB) | 2001-02-22 | — | — | WO | disclosed |
| CN-1284079-A | Novel compounds | ASTRA ZENECA BRITISH LTD (GB) | 2001-02-14 | — | — | CN | disclosed |
| WO-2001006261-A2 | SCREENING FOR THERAPEUTIC AGENTS BEING SCAP ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2001-01-25 | — | — | WO | disclosed |
| US-6143751-A | Pyridine derivatives and pharmaceutical compositions containing them | ASTRAZENECA UK LIMITED (GB) | 2000-11-07 | — | — | US | disclosed |
| EP-1036076-A1 | NOVEL COMPOUNDS | AstraZeneca UK Limited (GB) | 2000-09-20 | — | — | EP | disclosed |
| WO-1999029695-A1 | NOVEL COMPOUNDS | ASTRAZENECA UK LIMITED (GB) | 1999-06-17 | — | — | WO | disclosed |
| US-3950385-A | Preparation of nitronitrates | TEXACO INC. (US) | 1976-04-13 | — | — | US | disclosed |