Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 3/20 | 0.43 |
| ▸ | OXER1 | Q8TDS5 | 3/20 | 0.43 |
| ▸ | EP300 | Q09472 | 3/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | GABRE | P78334 | 1/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11016973 | 1.00 | SQOR (0.43) | SQOROXER1EP300ELANENAAA | |
| SCHEMBL11018469 | 1.00 | SQOR (0.43) | SQOROXER1EP300ELANENAAA | |
| SCHEMBL11015092 | 0.99 | EP300 (0.41) | SQOROXER1EP300ELANENAAA | |
| SCHEMBL1334906 | 0.82 | CYP11B1 (0.38) | EP300ELANEFGFR1GABRPGABRD | |
| SCHEMBL17371974 | 0.79 | PDE3A (0.36) | EP300FGFR1 | |
| SCHEMBL8450945 | 0.78 | PSMB11 (0.39) | FAAH | |
| SCHEMBL11015799 | 0.74 | CA2 (0.41) | FGFR1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL7165218 | 0.73 | SQOR (0.45) | SQOROXER1ELANENAAAFAAH | |
| SCHEMBL13975422 | 0.73 | FGFR1 (0.48) | EP300FGFR1 | |
| SCHEMBL13092480 | 0.72 | TLR8 (0.49) | SQOROXER1ELANENAAAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2148676-A1 | USE OF SAPACITABINE TO TREAT PROLIFERATIVE DISEASE | Cyclacel Limited (GB) | 2010-02-03 | — | — | EP | disclosed |
| WO-2009136158-A1 | PREPARATION OF INTERMEDIATES USEFUL IN THE SYNTHEIS OF 2'-CYANO-2'-DEOXY-N4-PALMITOYL-1-BETA-D-ARABINOFURANOSYLCYTOSINE | CYCLACEL LIMITED (GB) | 2009-11-12 | — | — | WO | disclosed |
| WO-2009136162-A1 | INTERMEDIATE AND PROCESSES INVOLVED IN THE PREPARATION OF 2 ' -CYANO-2 ' -DE0XY-N4-PALMIT0YL-1-BETA-ARABIN0FURAN0SYLCYTOSINE | CYCLACEL LIMITED (GB) | 2009-11-12 | — | — | WO | disclosed |
| WO-2008132443-A1 | USE OF SAPACITABINE TO TREAT PROLIFERATIVE DISEASE | CYCLACEL LIMITED (GB) | 2008-11-06 | — | — | WO | disclosed |
| EP-1962814-A2 | CRYSTALLINE PYRIMIDINE NUCLEOSIDE DERIVATIVES SUSPENSIONS IN CAPSULES | Cyclacel Limited (GB) | 2008-09-03 | — | — | EP | disclosed |
| EP-1945265-A1 | ANTIPROLIFERATIVE COMBINATION COMPRISING CYC-682 AND A CYTOTOXIC AGENT | Cyclacel Limited (GB) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007132228-A1 | COMBINATION OF CNDAC WITH A 2-SUBSTITUTED-4-HETER0ARYL-PYRIMIDINE AMINE AND USE THEREOF IN THE TREATMENT OF A PROLIFERATIVE DISORDER | CYCLACEL LIMITED (GB) | 2007-11-22 | — | — | WO | disclosed |
| WO-2007072061-A2 | CRYSTALLINE PYRIMIDINE NUCLEOSIDE DERIVATIVES SUSPENSIONS IN CAPSULES | CYCLACEL LIMITED (GB) | 2007-06-28 | — | — | WO | disclosed |
| WO-2007054731-A1 | ANTIPROLIFERATIVE COMBINATION COMPRISING CYC-682 AND A CYTOTOXIC AGENT | CYCLACEL LIMITED (GB) | 2007-05-18 | — | — | WO | disclosed |
| EP-0536936-B1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | SANKYO CO (JP) | 1996-08-14 | — | — | EP | disclosed |
| EP-0136693-A2 | Production of cytidine derivatives | Takeda Chemical Industries, Ltd. (JP) | 1985-04-10 | — | — | EP | disclosed |