⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1485705 | 0.87 | — | — | |
| SCHEMBL24290438 | 0.87 | — | — | |
| SCHEMBL12225902 | 0.86 | ADH1B (0.38) | — | |
| SCHEMBL1485934 | 0.84 | — | — | |
| SCHEMBL1485850 | 0.84 | ADH1B (0.55) | — | |
| SCHEMBL22047980 | 0.80 | — | — | |
| SCHEMBL10268917 | 0.80 | — | — | |
| SCHEMBL24289344 | 0.78 | LMNA (0.39) | — | |
| SCHEMBL13797755 | 0.76 | POLB (0.37) | — | |
| SCHEMBL21047749 | 0.76 | ADH1B (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3562487-B1 | METALLOENZYME INHIBITOR COMPOUNDS | JI XING PHARMACEUTICALS HONG KONG LTD (HK) | 2023-11-29 | — | — | EP | disclosed |
| EP-3983078-B1 | NEXT-GENERATION MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | RYVU THERAPEUTICS S A (PL) | 2023-11-15 | — | — | EP | disclosed |
| US-20230055741-A1 | FUNCTIONALIZED HETEROCYCLIC COMPOUNDS AS MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | Ryvu Therapeutics S.A. (PL) | 2023-02-23 | — | — | US | disclosed |
| EP-3967682-A1 | BISHETEROCYCLIC CARBONYL SUBSTITUTED DIHYDROPYRAZOLE COMPOUND, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | Genfleet Therapeutics (Shanghai) Inc. (CN) | 2022-03-16 | — | — | EP | disclosed |
| US-20220017471-A1 | FUNCTIONALITY INDEPENDENT LABELING OF ORGANIC COMPOUNDS | UNIV SHANGHAI TECHNOLOGY (CN) | 2022-01-20 | — | — | US | disclosed |
| EP-3577110-B1 | 8-OXETAN-3-YL-3,8-DIAZABICYCLO[3.2.1]OCTAN-3-YL SUBSTITUTED COMPOUNDS AS HIV INHIBITORS | GILEAD SCIENCES INC (US) | 2021-04-21 | — | — | EP | disclosed |
| EP-3799872-A1 | TETRAHYDROQUINOLINE DERIVATIVES FOR USE AS BET INHIBITORS | Forma Therapeutics, Inc. (US) | 2021-04-07 | — | — | EP | disclosed |
| WO-2020249773-A1 | NEXT-GENERATION MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | Ryvu Therapeutics S.A. (PL) | 2020-12-17 | — | — | WO | disclosed |
| WO-2020233669-A1 | INDOLE DERIVATIVE-CONTAINING INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海翰森生物医药科技有限公司 (CN) | 2020-11-26 | — | — | WO | disclosed |
| WO-2019023468-A1 | TYK2 INHIBITORS AND USES THEREOF | NIMBUS LAKSHMI, INC. (US) | 2019-01-31 | — | — | WO | disclosed |
| CN-102947315-A | Inhibitors of protein tyrosine kinase activity | METHYLGENE INC | 2013-02-27 | — | — | CN | disclosed |
| US-20120189539-A1 | BCL-2/BCL-XL INHIBITORS AND THERAPEUTIC METHODS USING THE SAME | THE REGENTS OF UNIVERSITY OF MICHIGAN (US) | 2012-07-26 | — | — | US | disclosed |
| US-8114200-B2 | Multi-dimensional portable gas chromatograph system | VPI Enigineering, Inc. (US) | 2012-02-14 | — | — | US | disclosed |
| CN-1960988-B | Compounds and compositions as protein kinase inhibitors | IRM LLC | 2012-01-25 | — | — | CN | disclosed |
| CN-102245028-A | Spiroheterocyclic N-oxypiperidines as pesticides | SYNGENTA PARTICIPATIONS AG | 2011-11-16 | — | — | CN | disclosed |
| CN-102177132-A | Optically active vinylcyclopropanecarboxylic acid derivative and method for producing optically active vinylcyclopropaneamino acid derivative | KANEGAFUCHI CHEMICAL IND | 2011-09-07 | — | — | CN | disclosed |
| US-20100250146-A1 | MULTI-DIMENSIONAL PORTABLE GAS CHROMATOGRAPH SYSTEM | ALLIANT TECHSYSTEMS INC. (US) | 2010-09-30 | — | — | US | disclosed |
| WO-2010041739-A1 | OPTICALLY ACTIVE VINYL-CYCLOPROPANE CARBOXYLIC ACID DERIVATIVE AND OPTICALLY ACTIVE VINYL-CYCLOPROPANE AMINO ACID DERIVATIVE MANUFACTURING METHOD | 株式会社カネカ (JP) | 2010-04-15 | — | — | WO | disclosed |
| CN-1960988-A | Compounds and compositions as protein kinase inhibitors | IRM LLC (BM) | 2007-05-09 | — | — | CN | disclosed |
| CN-1022183-C | Process for preparing quinolone carboxylic acid intermediates | PRIZER INC (US) | 1993-09-22 | — | — | CN | disclosed |