Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17022243 | 1.00 | HSD17B10 (0.52) | HSD17B10ALDH1A1TSHRPAOXKMT2A | |
| SCHEMBL8038150 | 1.00 | HSD17B10 (0.52) | HSD17B10ALDH1A1TSHRPAOXKMT2A | |
| SCHEMBL27018154 | 1.00 | HSD17B10 (0.52) | HSD17B10ALDH1A1TSHRPAOXKMT2A | |
| SCHEMBL13789337 | 1.00 | HSD17B10 (0.52) | HSD17B10ALDH1A1TSHRPAOXKMT2A | |
| SCHEMBL9391670 | 1.00 | HSD17B10 (0.52) | HSD17B10ALDH1A1TSHRPAOXKMT2A | |
| SCHEMBL12238110 | 1.00 | HSD17B10 (0.52) | HSD17B10ALDH1A1TSHRPAOXKMT2A | |
| SCHEMBL15140 | 1.00 | HSD17B10 (0.52) | HSD17B10ALDH1A1TSHRPAOXKMT2A | |
| Hydrochloric Acid SCHEMBL2150998 | 0.98 | ALDH1A1 (0.50) | HSD17B10ALDH1A1TSHRPAOXKMT2A | |
| Hydrochloric Acid SCHEMBL2192702 | 0.98 | ALDH1A1 (0.50) | HSD17B10ALDH1A1TSHRPAOXKMT2A | |
| Hydrochloric Acid SCHEMBL1128116 | 0.98 | ALDH1A1 (0.50) | HSD17B10ALDH1A1TSHRPAOXKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220233726-A1 | NOVEL RADIOLABELLED COMPOUNDS FOR DIAGNOSIS OR TREATMENT OF PROSTATE-SPECIFIC MEMBRANE ANTIGEN-EXPRESSING CANCER | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2022-07-28 | — | — | US | disclosed |
| US-20220218852-A1 | NOVEL RADIOLABELLED CXCR4-TARGETING COMPOUNDS FOR DIAGNOSIS AND THERAPY | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2022-07-14 | — | — | US | disclosed |
| US-20210402016-A1 | RADIOLABELED BOMBESIN-DERIVED COMPOUNDS FOR IN VIVO IMAGING OF GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR) AND TREATMENT OF GRPR-RELATED DISORDERS | PROVINCIAL HEALTH SERVICES AUTHORITY (CA) | 2021-12-30 | — | — | US | disclosed |
| US-20150110715-A1 | Double-Labeled Probe for Molecular Imaging and Use Thereof | RUPRECHT-KARLS-UNIVERSITAT HEIDELBERG (DE) | 2015-04-23 | — | — | US | disclosed |
| US-8420050-B2 | Gastrin releasing peptide compounds | BRACCO IMAGING S.P.A. (IT) | 2013-04-16 | — | — | US | disclosed |
| WO-2010029947-A1 | CONTRAST MEDIUM COMPOSITION AND PROCESS FOR PRODUCING SAME | 国立大学法人京都大学 (JP) | 2010-03-18 | — | — | WO | disclosed |
| US-20090175786-A1 | Gastrin Releasing Peptide Compounds | BRACCO IMAGING S.P.A. (IT) | 2009-07-09 | — | — | US | disclosed |
| US-20080008649-A1 | Gastrin Releasing Peptide Compounds | BRACCO IMAGING S.P.A. (IT) | 2008-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090175786-A1 | Gastrin Releasing Peptide Compounds | GRPR, SSTR5, GIPR | HSD17B10 4647/4885ALDH1A1 4399/4885TSHR 260/4885 |
| US-20080008649-A1 | Gastrin Releasing Peptide Compounds | GRPR, SSTR5, GIPR | HSD17B10 4647/4885ALDH1A1 4399/4885TSHR 260/4885 |
| US-20220218852-A1 | NOVEL RADIOLABELLED CXCR4-TARGETING COMPOUNDS FOR DIAGNOSIS AND THERAPY | CXCR4, CXCR1, FPR1 | HSD17B10 4478/4885ALDH1A1 3495/4885TSHR 264/4885 |
| US-20210402016-A1 | RADIOLABELED BOMBESIN-DERIVED COMPOUNDS FOR IN VIVO IMAGING OF GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR) AND TREATMENT OF GRPR-RELATED DISORDERS | GRPR, NPY1R, GIPR | HSD17B10 4833/4885ALDH1A1 4483/4885TSHR 50/4885 |
| US-20220233726-A1 | NOVEL RADIOLABELLED COMPOUNDS FOR DIAGNOSIS OR TREATMENT OF PROSTATE-SPECIFIC MEMBRANE ANTIGEN-EXPRESSING CANCER | KLK3, FOLH1, HRH3 | HSD17B10 2959/4885ALDH1A1 1996/4885TSHR 132/4885 |
| US-20150110715-A1 | Double-Labeled Probe for Molecular Imaging and Use Thereof | CD47, ANXA5, CD44 | HSD17B10 4215/4885ALDH1A1 1371/4885TSHR 1668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.