Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.54 |
| ▸ | TFEB | P19484 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.54 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2066256 | 1.00 | LMNA (0.62) | LMNAKDM4EKMT2APKMNFE2L2 | |
| Methacrylic Acid SCHEMBL8425085 | 0.94 | KMT2A (0.56) | LMNAKDM4EKMT2APKMNFE2L2 | |
| SCHEMBL11763791 | 0.87 | KDM4E (0.59) | LMNAKDM4EKMT2APKMNFE2L2 | |
| SCHEMBL11763787 | 0.87 | KDM4E (0.59) | LMNAKDM4EKMT2APKMNFE2L2 | |
| SCHEMBL20970610 | 0.85 | NFE2L2 (0.58) | LMNAKDM4EKMT2APKMNFE2L2 | |
| SCHEMBL8896493 | 0.84 | AKR1C3 (0.52) | LMNAKDM4EKMT2APKMMEN1 | |
| SCHEMBL11812444 | 0.84 | MAPT (0.56) | LMNAKDM4EKMT2APKMNFE2L2 | |
| SCHEMBL8896498 | 0.84 | AKR1C3 (0.52) | LMNAKDM4EKMT2APKMMEN1 | |
| SCHEMBL21198000 | 0.84 | KDM4E (0.56) | LMNAKDM4EKMT2APKMNFE2L2 | |
| SCHEMBL11812438 | 0.84 | MAPT (0.56) | LMNAKDM4EKMT2APKMNFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0578043-B1 | Glass fiber reinforced propylene polymer graft composition | MONTELL NORTH AMERICA INC (US) | 1998-11-18 | — | — | EP | claimed |
| EP-0522233-B1 | Impact resistant graft copolymers | HIMONT INC (US) | 1995-06-07 | — | — | EP | claimed |
| CN-110590529-A | Preparation method of 1-aryl-2-acetone compound | 浙江医药高等专科学校 | 2019-12-20 | — | — | CN | disclosed |
| EP-3233071-A1 | METHOD OF TREATING OR PREVENTING RAS-MEDIATED DISEASES | ADT Pharmaceuticals, Inc. (US) | 2017-10-25 | — | — | EP | disclosed |
| EP-3233794-A1 | INDENYL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF | ADT Pharmaceuticals, Inc. (US) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016100542-A1 | INDENYL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF | ADT PHARMACEUTICALS, INC. (US) | 2016-06-23 | — | — | WO | disclosed |
| WO-2016100546-A1 | METHOD OF TREATING OR PREVENTING RAS-MEDIATED DISEASES | ADT PHARMACEUTICALS, INC. (US) | 2016-06-23 | — | — | WO | disclosed |
| EP-1831323-B1 | USE OF A SINGLE OR DUAL-SIDED ADHESIVE TAPE FOR PROTECTING ELECTROCHROME LAYER SYSTEMS ON MIRRORS | TESA SE (DE) | 2014-02-26 | — | — | EP | disclosed |
| EP-2154216-A2 | Method for blister-free adhesion of highly transparent materials | tesa SE (DE) | 2010-02-17 | — | — | EP | disclosed |
| EP-2042578-A1 | Transparent adhesive tape | Tesa AG (DE) | 2009-04-01 | — | — | EP | disclosed |
| EP-2042579-A1 | Transparent adhesive tape | Tesa AG (DE) | 2009-04-01 | — | — | EP | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| EP-0975224-A1 | PROCESS AND COMPOSITIONS FOR ENHANCING RELIABILITY OF EXOGENOUS CHEMICAL SUBSTANCES APPLIED TO PLANTS | MONSANTO COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |
| US-6020287-A | USING MIXTURE OF HERBICIDE AND PHENYL-SUBSTITUTED OLEFIN COMPOUND | MONSANTO COMPANY (US) | 2000-02-01 | — | — | US | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
| EP-0841380-B1 | Method of making polymeric binders and use thereof in antifouling paints | WITCO GMBH (DE) | 1999-08-25 | — | — | EP | disclosed |
| WO-1998033385-A1 | PROCESS AND COMPOSITIONS FOR ENHANCING RELIABILITY OF EXOGENOUS CHEMICAL SUBSTANCES APPLIED TO PLANTS | MONSANTO COMPANY (US) | 1998-08-06 | — | — | WO | disclosed |
| EP-0841380-A1 | Method of making polymeric binders and use thereof in antifouling paints | Witco GmbH (DE) | 1998-05-13 | — | — | EP | disclosed |