Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.37 |
| ▸ | MGAM | O43451 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 5/20 | 0.36 |
| ▸ | SI | P14410 | 5/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 3/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL363538 | 0.85 | TDP1 (0.38) | TDP1ACLYBRD4MGAMGAA | |
| SCHEMBL364504 | 0.83 | GPBAR1 (0.40) | ACLYBRD4NR4A2GPBAR1NPC1 | |
| SCHEMBL363216 | 0.82 | GPBAR1 (0.39) | ACLYBRD4NR4A2GPBAR1NPC1 | |
| SCHEMBL14894610 | 0.82 | GPBAR1 (0.52) | TDP1BRD4GPBAR1MGAMGAA | |
| SCHEMBL1390186 | 0.82 | GPBAR1 (0.38) | TDP1BRD4NR4A2GPBAR1CTSA | |
| SCHEMBL369861 | 0.82 | GPBAR1 (0.55) | TDP1GPBAR1CTSAFFAR1S1PR1 | |
| SCHEMBL362317 | 0.81 | GPBAR1 (0.52) | BRD4GPBAR1CTSAFFAR1S1PR1 | |
| SCHEMBL14896301 | 0.81 | BRD4 (0.48) | TDP1BRD4GPBAR1MGAMGAA | |
| SCHEMBL363934 | 0.79 | GPBAR1 (0.47) | TDP1BRD4GPBAR1MGAMGAA | |
| SCHEMBL364664 | 0.78 | GAA (0.42) | BRD4GPBAR1MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |