Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.40 |
| ▸ | ACLY | P53396 | 2/20 | 0.38 |
| ▸ | CTSA | P10619 | 8/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | F9 | P00740 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL361844 | 0.92 | GPBAR1 (0.44) | GPBAR1ACLYCTSABRD4FFAR1 | |
| SCHEMBL363216 | 0.86 | GPBAR1 (0.39) | GPBAR1ACLYCTSABRD4NR4A2 | |
| SCHEMBL362317 | 0.85 | GPBAR1 (0.52) | GPBAR1CTSABRD4FFAR1 | |
| SCHEMBL362527 | 0.84 | GPBAR1 (0.55) | GPBAR1CTSABRD4MEN1KMT2A | |
| SCHEMBL363538 | 0.84 | TDP1 (0.38) | ACLYCTSABRD4PDE3BPDE3A | |
| SCHEMBL363787 | 0.83 | GPBAR1 (0.38) | GPBAR1BRD4FFAR1F9 | |
| SCHEMBL362646 | 0.83 | GPBAR1 (0.38) | GPBAR1BRD4FFAR1F9 | |
| SCHEMBL363296 | 0.83 | GPBAR1 (0.38) | GPBAR1BRD4FFAR1F9 | |
| SCHEMBL364524 | 0.83 | PTGS2 (0.36) | GPBAR1CTSABRD4NPC1F9 | |
| SCHEMBL362689 | 0.83 | TDP1 (0.38) | GPBAR1ACLYCTSABRD4NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | claimed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | claimed |
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |