Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3205838 | 0.82 | RAB9A (0.55) | MAPTALDH1A1SMN1; SMN2RAB9ACASP3 | |
| SCHEMBL3099247 | 0.80 | KMT2A (0.47) | MAPTALDH1A1HGFACSMN1; SMN2MEN1 | |
| SCHEMBL6417038 | 0.76 | HGFAC (0.55) | MAPTALDH1A1CRHBPCRHR2CES2 | |
| SCHEMBL254774 | 0.76 | CES1 (0.70) | MAPTALDH1A1CRHBPCRHR2CES2 | |
| SCHEMBL27459060 | 0.76 | CES1 (0.65) | MAPTALDH1A1CRHBPCRHR2CES2 | |
| SCHEMBL27499697 | 0.76 | CES1 (0.70) | ALDH1A1CRHBPCRHR2CES2CES1 | |
| SCHEMBL270426 | 0.75 | MEN1 (0.66) | MAPTALDH1A1CRHBPCRHR2CES2 | |
| SCHEMBL29588234 | 0.75 | MEN1 (0.66) | MAPTALDH1A1CRHBPCRHR2CES2 | |
| SCHEMBL270425 | 0.75 | MEN1 (0.66) | MAPTALDH1A1CRHBPCRHR2CES2 | |
| SCHEMBL9670086 | 0.75 | NPC1 (0.55) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2150588-A2 | POLYMERIC DYES BASED ON POLYMERIZABLE VINYL-GROUP CONTAINIG P-NITROPHENYL-AZO SALICYLIC ACID DERIVATIVES | Benz Research and Development Corporation (US) | 2010-02-10 | — | — | EP | disclosed |
| WO-2008134555-A2 | POLYMERIC DYES BASED ON POLYMERIZABLE VINYL-GROUP CONTAINING P-NITROPHENYL-AZO SALICYLIC ACID DERIVATIVES | BENZ RESEARCH AND DEVELOPMENT CORPORATION (US) | 2008-11-06 | — | — | WO | disclosed |