Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HGFAC | Q04756 | 3/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
| ▸ | PLAU | P00749 | 1/20 | 0.53 |
| ▸ | NOS1 | P29475 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NOS3 | P29474 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27372795 | 0.80 | KMT2A (0.70) | CES2CES1ALDH1A1NPC1RAB9A | |
| SCHEMBL4869749 | 0.78 | PLAU (0.64) | HGFACCES2CES1PLAUNOS1 | |
| SCHEMBL15058988 | 0.78 | TDP1 (0.58) | CES2CES1ALDH1A1NPC1RAB9A | |
| SCHEMBL3626933 | 0.76 | MAPT (0.55) | HGFACCES2CES1PLAUALDH1A1 | |
| SCHEMBL28184775 | 0.76 | KMT2A (0.60) | CES2CES1ALDH1A1NPC1RAB9A | |
| SCHEMBL5609313 | 0.75 | CES2 (0.58) | CES2CES1PLAUNOS1ALDH1A1 | |
| Guanidine SCHEMBL3748808 | 0.73 | KMT2A (0.67) | HGFACCES2CES1ALDH1A1RAB9A | |
| Methyl Carbamate SCHEMBL28555185 | 0.73 | CES2 (0.57) | CES2CES1PLAUNPC1RAB9A | |
| SCHEMBL5574678 | 0.73 | MEN1 (0.65) | HGFACPLAUNOS1NPC1RAB9A | |
| SCHEMBL254774 | 0.73 | CES1 (0.70) | CES2CES1ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050079218-A1 | Matrices for the stabilizing and controlled release of problematic substances | ACHIM GOPFERICH (DE) | 2005-04-14 | — | — | US | disclosed |
| US-5935995-A | POLY-, OLIGO- AND MONOSACCHARIDES OF DRUGS, E.G. NITROGEN MUSTARD GAS, QUININE AND DIPYRIDAMOLE; STABILITY; SLOW RELEASE; ANTIARTHITIC AGENTS; ENZYME INHIBITORS | HEOCHST AKTIENGESELLSCHAFT (DE) | 1999-08-10 | — | — | US | disclosed |