Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28971983 | 0.73 | MGLL (0.40) | MGLLCA12CA7CA14ADRA2A | |
| SCHEMBL27810211 | 0.71 | CA12 (0.32) | CA12CA7CA14 | |
| SCHEMBL3077427 | 0.69 | HSD17B10 (0.39) | CA12CA1CA9 | |
| SCHEMBL367039 | 0.69 | — | — | |
| SCHEMBL7399282 | 0.66 | MAPT (0.35) | MGLLCA12CA7CA14 | |
| SCHEMBL1535149 | 0.66 | CA12 (0.39) | MGLLCA12CA1CA2CA9 | |
| SCHEMBL4763981 | 0.65 | SMN1; SMN2 (0.39) | MGLLCA12CA7CA14 | |
| SCHEMBL18652280 | 0.65 | — | — | |
| SCHEMBL20590963 | 0.63 | CA12 (0.35) | MGLLCA12CA7CA14 | |
| SCHEMBL79194 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170878-A1 | NOVEL BENZAMIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING OSTEOPOROSIS COMPRISING THE SAME | Dong Wha Pharmaceutical Co., Ltd. (KR) | 2010-04-07 | — | — | EP | disclosed |
| WO-2009017346-A1 | NOVEL BENZAMIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING OSTEOPOROSIS COMPRISING THE SAME | DONG WHA PHARMACEUTICAL CO., LTD. (KR) | 2009-02-05 | — | — | WO | disclosed |