Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367925 | 0.90 | DPP7 (0.47) | DPP4DPP7DPP8GSK3BIDH1 | |
| SCHEMBL6638863 | 0.86 | DPP4 (0.53) | DPP4DPP7DPP8GSK3BIDH1 | |
| SCHEMBL1725026 | 0.84 | CHEK1 (0.52) | DPP4DPP7DPP8GSK3BIDH1 | |
| SCHEMBL14996239 | 0.84 | HCAR3 (0.54) | DPP4DPP7DPP8GSK3BIDH1 | |
| SCHEMBL3115089 | 0.84 | CHEK1 (0.52) | DPP4DPP7DPP8GSK3BIDH1 | |
| SCHEMBL1344707 | 0.83 | IDH1 (0.43) | DPP4DPP7DPP8GSK3BIDH1 | |
| SCHEMBL8352280 | 0.83 | CHEK1 (0.48) | DPP4DPP7DPP8GSK3BIDH1 | |
| SCHEMBL9405308 | 0.83 | HCAR3 (0.55) | DPP4DPP7DPP8GSK3BIDH1 | |
| SCHEMBL13617155 | 0.80 | DPP4 (0.43) | DPP4DPP7DPP8GSK3BIDH1 | |
| SCHEMBL1726095 | 0.80 | DPP7 (0.50) | DPP4DPP7DPP8GSK3BIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010032875-A2 | HETEROCYCLIC CARBOXAMIDE COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2010-03-25 | — | — | WO | disclosed |