SCHEMBL3627744

SCHEMBL3627744

CC=CC(=O)OCC(O)C[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.31
GSTP1 P09211 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9301566 0.84 TSHR (0.33) ATMGSTP1TSHR
SCHEMBL30376807 0.82 TSHR (0.50) TSHR
SCHEMBL235663 0.81
SCHEMBL331749 0.81 ATM (0.31) ATM
SCHEMBL20335453 0.80 TSHR (0.39) ATMGSTP1TSHR
SCHEMBL10538787 0.80 ATM (0.34) ATMGSTP1
SCHEMBL23581952 0.75 TSHR (0.35) ATMGSTP1TSHR
SCHEMBL347488 0.75 TSHR (0.35) ATMGSTP1TSHR
SCHEMBL5535259 0.75 TSHR (0.35) ATMGSTP1TSHR
SCHEMBL11811024 0.75 KDM4E (0.43) ATMGSTP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2180992-B1 PROCESS FOR MAKING OPHTHALMIC LENSES JOHNSON AND JOHNSON VISION CARE INC (US) 2019-08-14 EP disclosed
EP-3052140-B1 NON-SELF-ADHERENT COATING MATERIALS ROCHAL IND LLC (US) 2019-05-01 EP disclosed
US-8877882-B1 Non-self-adherent coating materials ROCHAL INDUSTRIES LLP (US) 2014-11-04 US disclosed
US-8714738-B2 Process for making ophthalmic lenses JOHNSON & JOHNSON VISION CARE, INC. (US) 2014-05-06 US disclosed
US-20130175722-A1 PROCESS FOR MAKING OPHTHALMIC LENSES JOHNSON & JOHNSON VISION CARE, INC. (US) 2013-07-11 US disclosed
US-8414804-B2 Process for making ophthalmic lenses JOHNSON & JOHNSON VISION CARE, INC. (US) 2013-04-09 US disclosed
EP-2180992-A2 PROCESS FOR MAKING OPHTHALMIC LENSES Johnson and Johnson Vision Care, Inc. (US) 2010-05-05 EP disclosed
WO-2007111973-A2 PROCESS FOR MAKING OPHTHALMIC LENSES JOHNSON & JOHNSON VISION CARE, INC. (US) 2007-10-04 WO disclosed
US-20070222094-A1 Process for making ophthalmic lenses JOHNSON & JOHNSON VISION CARE, INC. 2007-09-27 US disclosed