⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20335453 | 0.82 | TSHR (0.39) | — | |
| SCHEMBL3627744 | 0.81 | ATM (0.31) | — | |
| SCHEMBL5535259 | 0.77 | TSHR (0.35) | — | |
| SCHEMBL347488 | 0.77 | TSHR (0.35) | — | |
| SCHEMBL1284119 | 0.75 | ATM (0.31) | — | |
| SCHEMBL331749 | 0.75 | ATM (0.31) | — | |
| SCHEMBL14842526 | 0.75 | ATM (0.31) | — | |
| SCHEMBL11108878 | 0.75 | ATM (0.35) | — | |
| SCHEMBL27182144 | 0.74 | HCAR2 (0.32) | — | |
| SCHEMBL235662 | 0.74 | TSHR (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8349912-B2 | Crosslink agents and dual radical cure polymer | BAUSCH & LOMB INCORPORATED (US) | 2013-01-08 | — | — | US | claimed |
| US-20120004380-A1 | Crosslink Agents and Dual Radical Cure Polymer | BAUSCH HEALTH AMERICAS, INC. | 2012-01-05 | — | — | US | claimed |
| EP-3424965-B1 | CROSSLINK AGENTS AND ITS USE | BAUSCH & LOMB (US) | 2020-05-13 | — | — | EP | disclosed |
| EP-3424965-A1 | CROSSLINK AGENTS AND DUAL RADICAL CURE POLYMER | Bausch & Lomb Incorporated (US) | 2019-01-09 | — | — | EP | disclosed |
| EP-2167555-B1 | CROSSLINK AGENTS AND DUAL RADICAL CURE POLYMER | BAUSCH & LOMB (US) | 2018-10-10 | — | — | EP | disclosed |
| US-8349912-B2 | Crosslink agents and dual radical cure polymer | BAUSCH & LOMB INCORPORATED (US) | 2013-01-08 | — | — | US | disclosed |
| US-20120004380-A1 | Crosslink Agents and Dual Radical Cure Polymer | BAUSCH HEALTH AMERICAS, INC. | 2012-01-05 | — | — | US | disclosed |
| EP-2170966-A1 | CROSSLINK AGENTS AND DUAL RADICAL CURE POLYMER | Bausch & Lomb Incorporated (US) | 2010-04-07 | — | — | EP | disclosed |
| EP-2167555-A1 | CROSSLINK AGENTS AND DUAL RADICAL CURE POLYMER | Bausch & Lomb Incorporated (US) | 2010-03-31 | — | — | EP | disclosed |
| WO-2009111296-A1 | POLYSILOXANES AND POLYSILOXANE PREPOLYMERS WITH VINYL OR EPOXY FUNCTIONALITY | BAUSCH & LOMB INCORPORATED (US) | 2009-09-11 | — | — | WO | disclosed |
| WO-2009014923-A1 | CROSSLINK AGENTS AND DUAL RADICAL CURE POLYMER | BAUSCH & LOMB INCORPORATED (US) | 2009-01-29 | — | — | WO | disclosed |
| WO-2009009527-A1 | CROSSLINK AGENTS AND DUAL RADICAL CURE POLYMER | BAUSCH & LOMB INCORPORATED (US) | 2009-01-15 | — | — | WO | disclosed |