Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | HTR3B | O95264 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14815251 | 0.84 | CES2 (0.52) | CES2ALDH1A1MAPTHTTNPSR1 | |
| SCHEMBL31691810 | 0.84 | MAPT (0.60) | CES2HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL22655989 | 0.84 | MAPT (0.60) | CES2HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL10140894 | 0.82 | HTR3E (0.50) | CES2HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL10140895 | 0.82 | HTR3E (0.50) | CES2HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL169141 | 0.82 | HTR3E (0.50) | CES2HTR3EHTR3BHTR3AHTR3D | |
| Hydrochloric Acid SCHEMBL717668 | 0.81 | HTR3E (0.49) | CES2HTR3EHTR3BHTR3AHTR3D | |
| Hydrochloric Acid SCHEMBL27844889 | 0.81 | HTR3E (0.49) | CES2HTR3EHTR3BHTR3AHTR3D | |
| Hydrochloric Acid SCHEMBL717776 | 0.81 | HTR3E (0.49) | CES2HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL16892940 | 0.79 | CES2 (0.55) | CES2HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593424-A1 | NOVEL ARYLAMIDE DERIVATIVES HAVING ANTIANDROGENIC PROPERTIES | Medeia Therapeutics Ltd (FI) | 2013-05-22 | — | — | EP | claimed |
| WO-2012007644-A1 | NOVEL ARYLAMIDE DERIVATIVES HAVING ANTIANDROGENIC PROPERTIES | MEDEIA THERAPEUTICS LTD (FI) | 2012-01-19 | — | — | WO | claimed |
| EP-2593424-A1 | NOVEL ARYLAMIDE DERIVATIVES HAVING ANTIANDROGENIC PROPERTIES | Medeia Therapeutics Ltd (FI) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007644-A1 | NOVEL ARYLAMIDE DERIVATIVES HAVING ANTIANDROGENIC PROPERTIES | MEDEIA THERAPEUTICS LTD (FI) | 2012-01-19 | — | — | WO | disclosed |