Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 9/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 9/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.37 |
| ▸ | HTR2C | P28335 | 6/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | DRD1 | P21728 | 2/20 | 0.33 |
| ▸ | DRD5 | P21918 | 2/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.33 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.32 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.32 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.32 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL364452 | 0.90 | GPBAR1 (0.31) | — | |
| SCHEMBL363321 | 0.88 | TLR9 (0.36) | TLR9TLR7TLR8HTR2CHTR1A | |
| SCHEMBL362899 | 0.84 | TLR8 (0.40) | TLR9TLR7TLR8 | |
| SCHEMBL364180 | 0.82 | GPBAR1 (0.35) | — | |
| SCHEMBL364963 | 0.81 | GPBAR1 (0.32) | TLR7TLR8 | |
| SCHEMBL363805 | 0.81 | GPBAR1 (0.31) | — | |
| SCHEMBL364263 | 0.81 | GPBAR1 (0.31) | — | |
| SCHEMBL364539 | 0.80 | POLB (0.32) | — | |
| SCHEMBL364836 | 0.80 | POLB (0.32) | — | |
| SCHEMBL364583 | 0.79 | TLR9 (0.38) | TLR9TLR7TLR8HTR2CSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |