SCHEMBL3628323

SCHEMBL3628323

CC(SCC(F)(F)F)C(=O)Nc1ccc(C2=NOC(c3cc(Cl)c(Cl)c(Cl)c3)(C(F)(F)F)C2)cc1Cl

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
F2 P00734 2/20 0.31
F10 P00742 2/20 0.31
PRSS1 P07477 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3629991 0.91 ITGB1 (0.31) F2F10PRSS1
SCHEMBL3629194 0.90 CA1 (0.31) F2F10PRSS1
SCHEMBL3626388 0.86 CA1 (0.34) F2F10PRSS1
SCHEMBL3628329 0.86 CA1 (0.32) F2F10PRSS1
SCHEMBL3629974 0.78 PDE3B (0.30)
SCHEMBL3621526 0.77 F2 (0.34) F2F10PRSS1
SCHEMBL2522212 0.76 LMNA (0.36)
SCHEMBL3628687 0.75
SCHEMBL3625713 0.75 BACE1 (0.31) F2F10PRSS1
SCHEMBL2518676 0.75 LMNA (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2199287-A1 SUBSTITUTED ISOXAZOLINE COMPOUND AND PEST CONTROL AGENT Nissan Chemical Industries, Ltd. (JP) 2010-06-23 EP disclosed