SCHEMBL3628435

SCHEMBL3628435

COc1cccc2c1C(OC)C=C[CH]2

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.35
CA2 P00918 4/20 0.35
CA7 P43166 3/20 0.35
CA9 Q16790 3/20 0.35
CA12 O43570 2/20 0.35
CA14 Q9ULX7 2/20 0.35
CA4 P22748 1/20 0.35
ALDH1A1 P00352 2/20 0.33
TP53 P04637 2/20 0.33
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
ALOX12 P18054 1/20 0.33
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4308665 0.78 AOC3 (0.31) ALDH1A1KDM4EMAPTTDP1
SCHEMBL4310247 0.72 CA1 (0.35) CA1CA2CA7CA9CA12
SCHEMBL290935 0.71 RET (0.36)
SCHEMBL9038110 0.62 CA12 (0.39) CA1CA2CA7CA9CA12
SCHEMBL9870482 0.61 ABCB1 (0.64) CA1CA2CA7CA9CA12
SCHEMBL17401224 0.59 HTR2A (0.47) CA1CA2CA7CA9CA12
SCHEMBL17401223 0.59 HTR2A (0.47) CA1CA2CA7CA9CA12
SCHEMBL20221337 0.59 CA1 (0.35) CA1CA2CA7CA9CA12
SCHEMBL21202111 0.58 HTR2A (0.43) CA1CA2CA7CA9CA12
SCHEMBL34473301 0.58 SMN1; SMN2 (0.52) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2123695-B1 METAL THIETANE COMPOUND, POLYMERIZABLE COMPOSITION COMPRISING THE COMPOUND, RESIN, AND USE OF THE RESIN MITSUI CHEMICALS INC (JP) 2021-06-23 EP disclosed
EP-2161296-A1 Polymerisable compound und use thereof Mitsui Chemicals, Inc. (JP) 2010-03-10 EP disclosed