Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 7/20 | 0.34 |
| ▸ | RARG | P13631 | 6/20 | 0.33 |
| ▸ | RARA | P10276 | 5/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 5/20 | 0.32 |
| ▸ | RXRB | P28702 | 4/20 | 0.32 |
| ▸ | RXRG | P48443 | 3/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | BLVRB | P30043 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9899733 | 0.79 | THRB (0.35) | TP53MAPTMEN1CYP3A4KMT2A | |
| SCHEMBL31686125 | 0.78 | IDO1 (0.35) | TP53CYP3A4HTTIDO1 | |
| SCHEMBL16194297 | 0.73 | TP53 (0.33) | TP53CYP3A4 | |
| SCHEMBL7601520 | 0.68 | NPC1 (0.43) | RARBRARGRARATP53MAPT | |
| SCHEMBL19469462 | 0.68 | ALDH1A1 (0.43) | MAPTRXRARXRBRXRGMEN1 | |
| SCHEMBL11836524 | 0.66 | RARB (0.32) | RARBRARGRARARXRARXRB | |
| SCHEMBL11736019 | 0.65 | OPRL1 (0.31) | CYP3A4 | |
| Hydrochloric Acid SCHEMBL11703700 | 0.64 | OPRL1 (0.30) | — | |
| SCHEMBL29596749 | 0.64 | METAP1 (0.42) | MAPTMEN1CYP3A4KMT2A | |
| SCHEMBL16194435 | 0.64 | TP53 (0.33) | TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1565509-B1 | CATALYTIC COMPOSITION OF ORGANOTIN COMPOUNDS | CHEMTURA ORGANOMETALLICS GMBH (DE) | 2010-03-10 | — | — | EP | disclosed |
| US-7297804-B2 | Catalytic composition of organotin compounds | CHEMTURA ORGANOMETALICS GMBH (DE) | 2007-11-20 | — | — | US | disclosed |
| US-20060047101-A1 | Catalytic composition of organotin compounds | CHEMTURA ORGANOMETALLICS GMBH (DE) | 2006-03-02 | — | — | US | disclosed |
| EP-1565509-A1 | CATALYTIC COMPOSITION OF ORGANOTIN COMPOUNDS | Crompton GmbH (DE) | 2005-08-24 | — | — | EP | disclosed |
| WO-2004050742-A1 | CATALYTIC COMPOSITION OF ORGANOTIN COMPOUNDS | CROMPTON GMBH (DE) | 2004-06-17 | — | — | WO | disclosed |