SCHEMBL3628571

SCHEMBL3628571

O=c1c2c(oc3ccccc13)CCCC2

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 6/20 0.55
KDM4E B2RXH2 5/20 0.55
ALDH1A1 P00352 4/20 0.55
CYP3A4 P08684 3/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
HPGD P15428 2/20 0.55
CASP1 P29466 2/20 0.55
HSD17B10 Q99714 2/20 0.55
GLA P06280 1/20 0.55
MAPT P10636 1/20 0.55
PGAM1 P18669 1/20 0.55
CASP7 P55210 1/20 0.55
CYP1A2 P05177 1/20 0.46
CYP2C19 P33261 1/20 0.46
DDR2 Q16832 1/20 0.41
MEN1 O00255 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29576889 1.00 MAOA (0.55) MAOAKDM4EALDH1A1CYP3A4SMN1; SMN2
SCHEMBL31217612 0.98 MAOA (0.53) MAOAKDM4EALDH1A1CYP3A4SMN1; SMN2
SCHEMBL30591176 0.96 MAOA (0.55) MAOAKDM4EALDH1A1CYP3A4SMN1; SMN2
SCHEMBL10749276 0.96 MAOA (0.55) MAOAKDM4EALDH1A1CYP3A4SMN1; SMN2
SCHEMBL313890 0.84 CYP3A4 (0.56) MAOAKDM4EALDH1A1CYP3A4SMN1; SMN2
SCHEMBL30901816 0.82 MAOA (0.52) MAOAKDM4EALDH1A1CYP3A4SMN1; SMN2
SCHEMBL7481693 0.80 CYP3A4 (0.52) MAOAKDM4EALDH1A1CYP3A4SMN1; SMN2
SCHEMBL30901817 0.80 MAOA (0.42) MAOAKDM4EALDH1A1CYP3A4SMN1; SMN2
Bicarbonate SCHEMBL11464438 0.80 CYP1A2 (0.53) MAOAKDM4EALDH1A1CYP3A4SMN1; SMN2
SCHEMBL30281730 0.78 HTR6 (0.53) MAOAKDM4EALDH1A1CYP3A4SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118497312-A Preparation method of tetrahydroxanthone dimer compound and application of tetrahydroxanthone dimer compound in preparation of medicines for resisting liver cancer and cervical cancer 海南大学 2024-08-16 CN claimed
CN-114712345-B Application of tetrahydroxanthone dimer compound in preparation of antitumor drugs 海南大学 2024-01-26 CN claimed
CN-114712345-A Application of tetrahydroxanthone dimer compound in preparation of antitumor drugs 海南大学 2022-07-08 CN claimed
CN-114539200-A Synthesis method of tetrahydroxanthone 陕西科技大学 2022-05-27 CN claimed
CN-114292254-A Tetrahydrotoxaanthone dimer compound and preparation method and application thereof 浙江工业大学 2022-04-08 CN claimed
CN-110746446-B Dimeric tetrahydro xanthene compound and preparation method and application thereof 中国科学院华南植物园 2020-12-15 CN claimed
CN-110746446-A Dimeric tetrahydro xanthene compound and preparation method and application thereof 中国科学院华南植物园 2020-02-04 CN claimed
EP-0421829-B1 Benzopyranone-beta-D-thioxylosides, method for their preparation and their use FOURNIER IND & SANTE (FR) 1994-11-09 EP claimed
US-5169838-A Anticoagulants FOURNIER INDUSTRIE ET SANTE (FR) 1992-12-08 US claimed
EP-0421829-A1 Benzopyranone-beta-D-thioxylosides, method for their preparation and their use FOURNIER INDUSTRIE ET SANTE (FR) 1991-04-10 EP claimed
US-4290954-A ANTIALLERGENS, ANTIANAPHYLACTIC AGENTS, ANALGESICS, ANTIINFLAMMATORY AGENTS KOWA COMPANY LIMITED (JP) 1981-09-22 US claimed
JP-10175990-A None JP disclosed
JP-55062082-A None JP disclosed
WO-2025133657-A1 BIARYL-TYPE HETEROCYCLIC COMPOUNDS AND ANTI-BACTERIAL USES THEREOF DEBRECENI EGYETEM (HU) 2025-06-26 WO disclosed
CN-118497312-A Preparation method of tetrahydroxanthone dimer compound and application of tetrahydroxanthone dimer compound in preparation of medicines for resisting liver cancer and cervical cancer 海南大学 2024-08-16 CN disclosed
US-4290954-A ANTIALLERGENS, ANTIANAPHYLACTIC AGENTS, ANALGESICS, ANTIINFLAMMATORY AGENTS KOWA COMPANY LIMITED (JP) 1981-09-22 US disclosed
US-4290954-A ANTIALLERGENS, ANTIANAPHYLACTIC AGENTS, ANALGESICS, ANTIINFLAMMATORY AGENTS KOWA COMPANY LIMITED (JP) 1981-09-22 US disclosed
JP-S5562082-A TETRAHYDROXANTHONE DERIVATIVE KOWA CO 1980-05-10 JP disclosed
US-3862141-A 1-SUBSTITUTED 1,2,3,4-TETRAHYDROXANTHEN-9-ONES WARNER LAMBERT CO 1975-01-21 US disclosed
JP-S05562082-A 0001-01-01 JP disclosed