Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.63 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.57 |
| ▸ | BACE1 | P56817 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MPI | P34949 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 6/20 | 0.44 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2863552 | 0.89 | ALOX5 (0.65) | ALOX5ESR2BACE1CYP26A1ALDH1A1 | |
| SCHEMBL2860952 | 0.88 | ALOX5 (0.63) | ALOX5ESR2BACE1KMT2ACYP26A1 | |
| SCHEMBL21247610 | 0.87 | HSD17B10 (0.48) | ALOX5ESR2MMP3ESR1 | |
| SCHEMBL1071089 | 0.84 | ALOX5 (0.61) | ALOX5ESR2BACE1KMT2ACYP26A1 | |
| SCHEMBL27678594 | 0.84 | ALOX5 (0.59) | ALOX5ESR2BACE1KMT2ACYP26A1 | |
| SCHEMBL1292805 | 0.84 | ALOX5 (0.59) | ALOX5ESR2BACE1KMT2ACYP26A1 | |
| Hydrochloric Acid SCHEMBL27678589 | 0.82 | ALOX5 (0.57) | ALOX5ESR2BACE1KMT2ACYP26A1 | |
| SCHEMBL19826793 | 0.82 | HSD17B1 (0.57) | ALOX5ESR2KMT2AMEN1ESR1 | |
| SCHEMBL10598993 | 0.81 | ALOX5 (0.55) | ALOX5ESR2BACE1CYP26A1 | |
| SCHEMBL28600186 | 0.81 | ALOX5 (0.55) | ALOX5ESR2BACE1CYP26A1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2181173-A1 | LIQUID CRYSTAL DISPLAY | Merck Patent GmbH (DE) | 2010-05-05 | — | — | EP | disclosed |
| WO-2009030329-A1 | LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2009-03-12 | — | — | WO | disclosed |