Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | EYA2 | O00167 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8957835 | 0.85 | TDP1 (0.38) | TDP1EYA2APPACEDRD3 | |
| SCHEMBL24910128 | 0.82 | KDM4E (0.30) | TDP1KDM4E | |
| SCHEMBL11303647 | 0.81 | TDP1 (0.38) | TDP1EYA2APPACEDRD3 | |
| SCHEMBL11306734 | 0.79 | TDP1 (0.37) | TDP1EYA2APPACEDRD3 | |
| SCHEMBL377313 | 0.76 | NPSR1 (0.41) | TDP1EYA2APPACEDRD3 | |
| SCHEMBL5007664 | 0.75 | NR1D1 (0.36) | TDP1 | |
| SCHEMBL18674465 | 0.74 | EGLN1 (0.36) | TDP1EYA2APPACEDRD3 | |
| SCHEMBL13131641 | 0.74 | KDM4E (0.39) | TDP1KDM4ELMNATSHRHRH3 | |
| SCHEMBL15104854 | 0.73 | CA12 (0.41) | TDP1KDM4ELMNACYP2C19CA1 | |
| SCHEMBL13267939 | 0.73 | KDM4E (0.40) | KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010055207-A1 | CHELATING, CHELATING AGENTS AND CONJUGATES DERIVER THEREOF | WALLAC OY (FI) | 2010-05-20 | — | — | WO | disclosed |