SCHEMBL3629039

SCHEMBL3629039

C=CCP(CC=C)c1ccc(OC)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.52
TP53 P04637 1/20 0.52
CYP3A4 P08684 1/20 0.52
ALOX15 P16050 1/20 0.52
TSHR P16473 1/20 0.52
ALOX12 P18054 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
PKM P14618 1/20 0.45
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44
TGM2 P21980 1/20 0.41
NR1I2 O75469 1/20 0.39
ACHE P22303 1/20 0.38
LMNA P02545 1/20 0.38
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10549801 0.84 ALDH1A1 (0.52) ALDH1A1TP53CYP3A4ALOX15TSHR
SCHEMBL3625373 0.77 NPSR1 (0.37) ALDH1A1SMN1; SMN2PKMTGM2ACHE
SCHEMBL11213027 0.74 CA1 (0.52) ALDH1A1CYP3A4CA12CA1CA2
SCHEMBL17529672 0.73 CA1 (0.46) CA12CA1CA2CA7CA9
SCHEMBL11569712 0.72 CA1 (0.50) ALDH1A1CYP3A4CA12CA1CA2
SCHEMBL3629171 0.72 PYCR1 (0.37) SMN1; SMN2TGM2LMNACYP2A6CES2
SCHEMBL3623258 0.72 CA1 (0.50) ALDH1A1TP53CYP3A4ALOX15TSHR
SCHEMBL624569 0.72 CYP3A4 (0.39) ALDH1A1CYP3A4TSHRSMN1; SMN2TGM2
SCHEMBL17529757 0.71 CA1 (0.48) CA12CA1CA2CA7CA9
Bromide SCHEMBL7610464 0.70 CYP3A4 (0.38) ALDH1A1CYP3A4TSHRSMN1; SMN2TGM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1222497-B1 UV-ABSORBING SUPPORT LAYERS AND FLEXOGRAPHIC PRINTING ELEMENTS COMPRISING SAME MACDERMID PRINTING SOLUTIONS (US) 2010-08-11 EP claimed
US-RE39835-E1 UV-absorbing support layers and flexographic printing elements comprising same MACDERMID GRAPHICS SOLUTIONS, LLC 2007-09-11 US claimed
EP-1222497-A4 UV-ABSORBING SUPPORT LAYERS AND FLEXOGRAPHIC PRINTING ELEMENTS COMPRISING SAME MACDERMID GRAPHIC ARTS INC (US) 2006-12-27 EP claimed
JP-2003511742-A 2003-03-25 JP claimed
EP-1222497-A1 UV-ABSORBING SUPPORT LAYERS AND FLEXOGRAPHIC PRINTING ELEMENTS COMPRISING SAME Macdermid Graphic Arts, Inc. (US) 2002-07-17 EP claimed
US-6413699-B1 LAYER OF SOLID PHOTOCURABLE MATERIAL COMPRISES A PHOSPHINE COMPOUND AS AN OXYGEN SCAVENGER MACDERMID GRAPHIC ARTS, INC. 2002-07-02 US claimed
US-20020058196-A1 UV-ABSORBING SUPPORT LAYERS AND FLEXOGRAPHIC PRINTING ELEMENTS COMPRISING SAME MACDERMID GRAPHICS SOLUTIONS, LLC 2002-05-16 US claimed
WO-2001027696-A1 UV-ABSORBING SUPPORT LAYERS AND FLEXOGRAPHIC PRINTING ELEMENTS COMPRISING SAME MACDERMID GRAPHIC ARTS, INC. (US) 2001-04-19 WO claimed
US-6007967-A Methods for off-contact imaging solid printing plates POLYFIBRON TECHNOLOGIES, INC. (US) 1999-12-28 US claimed
US-RE39835-E1 UV-absorbing support layers and flexographic printing elements comprising same MACDERMID GRAPHICS SOLUTIONS, LLC 2007-09-11 US disclosed
US-6413699-B1 LAYER OF SOLID PHOTOCURABLE MATERIAL COMPRISES A PHOSPHINE COMPOUND AS AN OXYGEN SCAVENGER MACDERMID GRAPHIC ARTS, INC. 2002-07-02 US disclosed
US-20020058196-A1 UV-ABSORBING SUPPORT LAYERS AND FLEXOGRAPHIC PRINTING ELEMENTS COMPRISING SAME MACDERMID GRAPHICS SOLUTIONS, LLC 2002-05-16 US disclosed
US-6007967-A Methods for off-contact imaging solid printing plates POLYFIBRON TECHNOLOGIES, INC. (US) 1999-12-28 US disclosed
US-5418112-A Stereolithography W. R. GRACE & CO.-CONN. (US) 1995-05-23 US disclosed
WO-1995013565-A1 PHOTOSENSITIVE COMPOSITIONS USEFUL IN THREE-DIMENSIONAL PART-BUILDING AND HAVING IMPROVED PHOTOSPEED W.R. GRACE & CO.-CONN. (US) 1995-05-18 WO disclosed
EP-0102312-A1 Unsaturated polyurethanes THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-03-07 EP disclosed
EP-0089913-A1 Unsaturated polyester and process for making an unsaturated polyester THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-09-28 EP disclosed
US-4221646-A Treated polyetherurethane photopolymer composition containing triaryl phosphine THE GOODYEAR TIRE & RUBBER COMPANY (US) 1980-09-09 US disclosed