SCHEMBL3629052

SCHEMBL3629052

Clc1cc(Br)ccc1-c1ncc[nH]1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MC4R P32245 2/20 0.49
ADRA2A P08913 4/20 0.49
ADRA2C P18825 3/20 0.49
ADRA2B P18089 2/20 0.49
NISCH Q9Y2I1 2/20 0.40
MTOR P42345 1/20 0.40
ADK P55263 1/20 0.40
CSNK1A1 P48729 1/20 0.38
TYRO3 Q06418 1/20 0.38
DYRK1B Q9Y463 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
ALDH1A1 P00352 2/20 0.36
PTGES O14684 1/20 0.35
PIM1 P11309 1/20 0.35
CSNK2A2 P19784 1/20 0.35
CSNK2B P67870 1/20 0.35
PIM3 Q86V86 1/20 0.35
PIM2 Q9P1W9 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27901189 0.88 MC4R (0.48) MC4RADRA2AADRA2CADRA2BNISCH
SCHEMBL4974089 0.82 MC4R (0.40) MC4RADRA2AADRA2CADRA2BNISCH
SCHEMBL3631532 0.81 RAB9A (0.50) NISCHMTORADKCSNK1A1TYRO3
SCHEMBL27559815 0.81 GSK3B (0.42) MC4RADRA2AADRA2CADRA2BCSNK1A1
SCHEMBL1485057 0.80 ADRA2A (0.50) MC4RADRA2AADRA2CADRA2BNISCH
SCHEMBL29793016 0.80 ADRA2A (0.50) MC4RADRA2AADRA2CADRA2BNISCH
SCHEMBL8536056 0.79 MC4R (0.49) MC4RADRA2AADRA2CADRA2BNISCH
SCHEMBL17926901 0.79 ADRA2A (0.49) MC4RADRA2AADRA2CADRA2BNISCH
SCHEMBL21657456 0.79 ADRA2A (0.49) MC4RADRA2AADRA2CADRA2BNISCH
SCHEMBL5914842 0.79 ADRA2A (0.49) MC4RADRA2AADRA2CADRA2BNISCH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2144898-A2 HETEROCYCLIC HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME Sumitomo Chemical Company, Limited (JP) 2010-01-20 EP disclosed
WO-2008130021-A2 HETEROCYCLIC HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-10-30 WO disclosed
EP-1937664-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME Sumitomo Chemical Company, Limited (JP) 2008-07-02 EP disclosed
WO-2007043677-A9 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL CO (JP) 2007-06-07 WO disclosed
WO-2007043677-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-04-19 WO disclosed