SCHEMBL3629149

SCHEMBL3629149

Cc1ccccc1OCC(C)O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.68
CYP1A2 P05177 2/20 0.68
ADRB2 P07550 1/20 0.63
ADRB1 P08588 1/20 0.63
ADRB3 P13945 1/20 0.63
ALOX15 P16050 1/20 0.62
LMNA P02545 5/20 0.58
KMT2A Q03164 4/20 0.58
MEN1 O00255 3/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
SCN4A P35499 2/20 0.56
CYP3A4 P08684 1/20 0.54
CYP2D6 P10635 1/20 0.54
MAPT P10636 1/20 0.54
CYP2C9 P11712 1/20 0.54
HPGD P15428 1/20 0.54
CYP2C19 P33261 1/20 0.54
ALDH1A1 P00352 2/20 0.51
NPSR1 Q6W5P4 1/20 0.50
NPY1R P25929 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11303021 0.87 LMNA (0.65) KDM4ECYP1A2ADRB2ADRB1ADRB3
SCHEMBL18423672 0.86 KDM4E (0.82) KDM4ECYP1A2ADRB2ADRB1ADRB3
SCHEMBL7120229 0.86 KDM4E (0.70) KDM4ECYP1A2ADRB2ADRB1ADRB3
SCHEMBL9120285 0.85 KMT2A (0.50) KDM4ECYP1A2ADRB2ADRB1ADRB3
SCHEMBL14290588 0.85 KMT2A (0.50) KDM4ECYP1A2ADRB2ADRB1ADRB3
SCHEMBL8047112 0.83 KDM4E (0.61) KDM4ECYP1A2ADRB2ADRB1ADRB3
SCHEMBL17813019 0.83 KDM4E (0.61) KDM4ECYP1A2ADRB2ADRB1ADRB3
SCHEMBL11104803 0.82 KDM4E (0.66) KDM4ECYP1A2ADRB2ADRB1ADRB3
SCHEMBL10635992 0.82 ALOX15 (0.47) KDM4ECYP1A2ADRB2ADRB1ADRB3
Mephenesin SCHEMBL6482337 0.81 CYP1A2 (1.00) KDM4ECYP1A2ADRB2ADRB1ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11083192-B2 Fertilizer and agrochemical formulation MITSUI CHEMICALS AGRO, INC. (JP) 2021-08-10 US claimed
US-20190320651-A1 FERTILIZER AND AGROCHEMICAL FORMULATION MITSUI CHEMICALS AGRO, INC. (JP) 2019-10-24 US claimed
US-10375951-B2 Fertilizer and agrochemical formulation MITSUI CHEMICALS AGRO, INC. (JP) 2019-08-13 US claimed
US-20180139954-A1 FERTILIZER AND AGROCHEMICAL FORMULATION MITSUI CHEMICALS AGRO, INC. (JP) 2018-05-24 US claimed
WO-2016170784-A1 FERTILIZER AND AGROCHEMICAL FORMULATION MITSUI CHEMICALS AGRO, INC. (JP) 2016-10-27 WO claimed
US-6248314-B1 Hair dye composition having a particular buffer capacity and containing an alkylene carbonate KAO CORPORATION (JP) 2001-06-19 US claimed
EP-1022014-A1 Hair dye composition Kao Corporation (JP) 2000-07-26 EP claimed
US-11541041-B1 Compounds that interact with the Ras superfamily for the treatment of cancers, inflammatory diseases, Rasopathies, and fibrotic disease SHY Therapeutics LLC (US) 2023-01-03 US disclosed
US-11538992-B2 Formulation of an organic functional material MERCK PATENT GMBH (DE) 2022-12-27 US disclosed
WO-2022019035-A1 INK SET AND MAINTENANCE METHOD 富士フイルム株式会社 2022-01-27 WO disclosed
US-11083192-B2 Fertilizer and agrochemical formulation MITSUI CHEMICALS AGRO, INC. (JP) 2021-08-10 US disclosed
EP-3532565-B1 FORMULATION OF AN ORGANIC FUNCTIONAL MATERIAL MERCK PATENT GMBH (DE) 2021-04-21 EP disclosed
EP-3532565-B1 FORMULATION OF AN ORGANIC FUNCTIONAL MATERIAL MERCK PATENT GMBH (DE) 2021-04-21 EP disclosed
US-6248314-B1 Hair dye composition having a particular buffer capacity and containing an alkylene carbonate KAO CORPORATION (JP) 2001-06-19 US disclosed
CN-1284941-A Novel antiarrhythmic compounds PHARMACEUTICAL RES INST PUBLIC (HU) 2001-02-21 CN disclosed
WO-2000076984-A2 NOVEL COMPOUNDS, THEIR USE AND PREPARATION BIOVITRUM AB (SE) 2000-12-21 WO disclosed
EP-1022014-A1 Hair dye composition Kao Corporation (JP) 2000-07-26 EP disclosed
EP-0492615-B1 Process for producing biguanide derivative IDEMITSU KOSAN CO (JP) 1995-03-08 EP disclosed
US-5286905-A Heating hydrogen halide salt of phenoxyalkylamine with dicyandiamide in paraffinic hydrocarbon solvent IDEMITSU KOSAN COMPANY LIMITED (JP) 1994-02-15 US disclosed
EP-0492615-A1 Process for producing biguanide derivative IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-07-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11541041-B1 Compounds that interact with the Ras superfamily for the treatment of cancers, inflammatory diseases, Rasopathies, and fibrotic disease HRAS, KRAS, NRAS KDM4E 4215/4885CYP1A2 4764/4885ADRB2 3974/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.