SCHEMBL3629282

SCHEMBL3629282

CCCC(=O)C(C(C)=O)C(=O)OCC.[Zr]

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
LMNA P02545 1/20 0.44
HSD17B10 Q99714 1/20 0.44
ALOX15 P16050 1/20 0.33
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
SOAT1 P35610 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MAPT P10636 1/20 0.32
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
GLO1 Q04760 1/20 0.31
CYP1A2 P05177 1/20 0.31
TRPA1 O75762 1/20 0.31
FFAR3 O14843 1/20 0.31
HDAC3 O15379 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3297474 0.98 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL27795733 0.96 ALDH1A1 (0.44) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL27955574 0.87 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL4612571 0.87 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL10861271 0.86 ALDH1A1 (0.43) ALDH1A1LMNAHSD17B10CES2CES1
SCHEMBL9247380 0.86 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL3126142 0.85 ALDH1A1 (0.44) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL14065156 0.83 CES2 (0.48) MAPTCES2CES1
SCHEMBL14065174 0.83 CES2 (0.48) MAPTCES2CES1
SCHEMBL12749831 0.83 CES2 (0.48) MAPTCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160231657-A1 Electrophotographic Photoreceptor, Process Cartridge and Image Forming Apparatus FUJI XEROX CO., LTD. (JP) 2016-08-11 US disclosed
US-7702256-B2 Image-forming apparatus including an electrophotographic photoreceptor having an undercoat layer with metal oxide particles and an acceptor compound FUJI XEROX CO., LTD. (JP) 2010-04-20 US disclosed
US-20060014092-A1 Electrophotographic photoreceptor, electrophotographic cartridge and electrophotographic apparatus FUJI XEROX CO., LTD. (JP) 2006-01-19 US disclosed
US-20060013616-A1 Image forming apparatus and process cartridge CITIBANK, N.A., AS COLLATERAL AGENT 2006-01-19 US disclosed