Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.31 |
| ▸ | STK17B | O94768 | 1/20 | 0.31 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29920335 | 1.00 | P2RX3 (0.32) | P2RX3GAAMCOLN3STK17BSTK17A | |
| SCHEMBL1397666 | 0.83 | P2RX3 (0.38) | P2RX3STK17BSTK17ACNR2ALDH1A1 | |
| SCHEMBL29594217 | 0.83 | P2RX3 (0.38) | P2RX3STK17BSTK17ACNR2ALDH1A1 | |
| SCHEMBL15584044 | 0.80 | CA12 (0.35) | STK17BSTK17ACNR2 | |
| SCHEMBL30907180 | 0.77 | SYK (0.34) | P2RX3GAASTK17BSTK17ANPSR1 | |
| SCHEMBL30373155 | 0.76 | GAA (0.35) | P2RX3GAAMCOLN3NPSR1AAK1 | |
| SCHEMBL3634187 | 0.75 | KMT2A (0.43) | GAANPSR1KDM4EALDH1A1POLB | |
| SCHEMBL17947811 | 0.75 | FDFT1 (0.33) | CNR2ALDH1A1 | |
| SCHEMBL30349062 | 0.74 | GPBAR1 (0.41) | P2RX3GAAMCOLN3AAK1 | |
| SCHEMBL19675997 | 0.73 | CA12 (0.35) | STK17BSTK17ASYKAAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858707-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |
| EP-2155735-A2 | TRIAZOLYL AMINOPYRIMIDINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008144222-A2 | TRIAZOLYL AMINOPYRIMIDINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2008-11-27 | — | — | WO | disclosed |