Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 3/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | STK17B | O94768 | 1/20 | 0.31 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.30 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15584044 | 0.86 | CA12 (0.35) | CA12CA1CA7CA14F2 | |
| SCHEMBL15584043 | 0.78 | PGK1 (0.36) | — | |
| SCHEMBL18944295 | 0.73 | HCAR3 (0.42) | CA12HDAC1 | |
| SCHEMBL29920335 | 0.73 | P2RX3 (0.32) | SYKAAK1STK17BSTK17A | |
| SCHEMBL3629295 | 0.73 | P2RX3 (0.32) | SYKAAK1STK17BSTK17A | |
| SCHEMBL12439073 | 0.73 | GPBAR1 (0.41) | AAK1USP30GPBAR1 | |
| SCHEMBL18068202 | 0.73 | STK17B (0.34) | SYKAAK1USP30STK17BSTK17A | |
| SCHEMBL27681546 | 0.72 | TRPA1 (0.39) | SYKNFKB1NFKB2RELACPB2 | |
| SCHEMBL30907180 | 0.71 | SYK (0.34) | SYKAAK1HDAC1HDAC8HDAC6 | |
| SCHEMBL24344478 | 0.70 | PIK3CD (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2840080-B1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND OR SALT THEREOF | FUJIFILM CORP (JP) | 2017-12-06 | — | — | EP | disclosed |