Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylonitrile SCHEMBL9562747 | 0.90 | THRB (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| Water SCHEMBL7119412 | 0.88 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| Acrylonitrile SCHEMBL4005713 | 0.87 | TSHR (0.64) | TSHRTHRBPOLBAPEX1HTT | |
| Acrylonitrile SCHEMBL11546320 | 0.87 | THRB (0.43) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL11414270 | 0.86 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| Propene SCHEMBL28204235 | 0.86 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL15480 | 0.86 | TSHR (0.64) | TSHRTHRBPOLBAPEX1HTT | |
| Acrylonitrile SCHEMBL28108185 | 0.85 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| Vinyl Chloride SCHEMBL3083512 | 0.84 | TSHR (0.55) | TSHRTHRBPOLBAPEX1HTT | |
| Acrylonitrile SCHEMBL23071585 | 0.84 | ALDH1A1 (0.47) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104745011-B | AQUEOUS STAIN BLOCKING COATING COMPOSITIONS | 巴斯夫欧洲公司 | 2017-05-03 | — | — | CN | disclosed |
| EP-2014724-B9 | Wettable hydrogels comprising acyclic polyamides | JOHNSON & JOHNSON VISION CARE (US) | 2016-09-14 | — | — | EP | disclosed |
| EP-2014724-B1 | Wettable hydrogels comprising acyclic polyamides | JOHNSON & JOHNSON VISION CARE (US) | 2016-04-06 | — | — | EP | disclosed |
| US-8222353-B2 | Wettable hydrogels comprising acyclic polyamides | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2012-07-17 | — | — | US | disclosed |
| US-20110294914-A1 | WETTABLE HYDROGELS COMPRISING ACYCLIC POLYAMIDES | JOHNSON & JOHNSON VISION CARE, INC. | 2011-12-01 | — | — | US | disclosed |
| US-7786185-B2 | Wettable hydrogels comprising acyclic polyamides | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2010-08-31 | — | — | US | disclosed |
| EP-1720943-B1 | WETTABLE HYDROGELS COMPRISING ACYCLIC POLYAMIDES | JOHNSON & JOHNSON VISION CARE (US) | 2009-02-11 | — | — | EP | disclosed |
| EP-2014724-A1 | Wettable hydrogels comprising acyclic polyamides | Johson & Johnson Vision Care Inc. (US) | 2009-01-14 | — | — | EP | disclosed |
| US-20080045612-A1 | Wettable hydrogels comprising acyclic polyamides | JOHNSON & JOHNSON VISION CARE, INC | 2008-02-21 | — | — | US | disclosed |
| EP-1720943-A1 | WETTABLE HYDROGELS COMPRISING ACYCLIC POLYAMIDES | Johnson & Johnson Vision Care, Inc. (US) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005092987-A1 | WETTABLE HYDROGELS COMPRISING ACYCLIC POLYAMIDES | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2005-10-06 | — | — | WO | disclosed |