Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.58 |
| ▸ | ANO1 | Q5XXA6 | 7/20 | 0.55 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.54 |
| ▸ | PTPRC | P08575 | 1/20 | 0.53 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.53 |
| ▸ | PTPA | Q15257 | 1/20 | 0.53 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3627300 | 0.88 | MAPT (0.72) | THRBMEN1RAB9AKMT2ANPC1 | |
| SCHEMBL3629109 | 0.88 | MAPT (0.72) | THRBMEN1RAB9AKMT2ANPC1 | |
| SCHEMBL3620747 | 0.88 | THRB (0.80) | THRBMEN1RAB9AKMT2ANPC1 | |
| SCHEMBL3630314 | 0.81 | MEN1 (0.78) | THRBMEN1RAB9AKMT2ANPC1 | |
| SCHEMBL3630934 | 0.81 | MEN1 (0.78) | MEN1RAB9AKMT2ANPC1ANO1 | |
| SCHEMBL3629623 | 0.81 | MEN1 (0.80) | MEN1RAB9AKMT2ANPC1TP53 | |
| SCHEMBL3630211 | 0.81 | MEN1 (0.78) | MEN1RAB9AKMT2ANPC1ANO1 | |
| SCHEMBL3628382 | 0.81 | MEN1 (0.80) | MEN1RAB9AKMT2ANPC1TP53 | |
| SCHEMBL3629758 | 0.81 | MEN1 (0.80) | MEN1RAB9AKMT2ANPC1MAPT | |
| SCHEMBL21247385 | 0.81 | TP53 (0.72) | THRBMEN1RAB9AKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2200607-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | Calcimedica, Inc. (US) | 2010-06-30 | — | — | EP | disclosed |
| WO-2009035818-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA, INC. (US) | 2009-03-19 | — | — | WO | disclosed |