SCHEMBL3629423

SCHEMBL3629423

Cc1ccc(N(c2ccc(C)cc2)c2ccc(C)cc2)cc1.Cc1ccc(N(c2ccc(C)cc2)c2ccc(C=Cc3ccc(C=Cc4ccc(N(c5ccc(C)cc5)c5ccc(C)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 4/20 0.56
RELA Q04206 2/20 0.52
ALOX5 P09917 1/20 0.48
PTGS1 P23219 1/20 0.48
PTGS2 P35354 1/20 0.48
CA1 P00915 1/20 0.46
ALDH1A1 P00352 1/20 0.46
TSHR P16473 1/20 0.46
APP P05067 3/20 0.45
MEN1 O00255 3/20 0.45
RAB9A P51151 3/20 0.45
KMT2A Q03164 3/20 0.45
APOBEC3A P31941 2/20 0.45
APOBEC3G Q9HC16 2/20 0.45
NPC1 O15118 2/20 0.44
GAA P10253 1/20 0.44
GFER P55789 1/20 0.44
CYP2A6 P11509 1/20 0.44
TUBB4A P04350 1/20 0.44
TUBB P07437 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5494929 1.00 NFE2L2 (0.56) NFE2L2RELAALOX5PTGS1PTGS2
SCHEMBL5953353 1.00 NFE2L2 (0.56) NFE2L2RELAALOX5PTGS1PTGS2
SCHEMBL5937913 1.00 NFE2L2 (0.56) NFE2L2RELAALOX5PTGS1PTGS2
SCHEMBL5937944 1.00 NFE2L2 (0.56) NFE2L2RELAALOX5PTGS1PTGS2
SCHEMBL5492449 1.00 NFE2L2 (0.56) NFE2L2RELAALOX5PTGS1PTGS2
SCHEMBL16489726 1.00 NFE2L2 (0.56) NFE2L2RELAALOX5PTGS1PTGS2
SCHEMBL10015739 1.00 NFE2L2 (0.56) NFE2L2RELAALOX5PTGS1PTGS2
SCHEMBL75905 1.00 NFE2L2 (0.56) NFE2L2RELAALOX5PTGS1PTGS2
SCHEMBL20663990 1.00 NFE2L2 (0.56) NFE2L2RELAALOX5PTGS1PTGS2
SCHEMBL75906 1.00 NFE2L2 (0.56) NFE2L2RELAALOX5PTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2149283-A1 LAMP WITH ADJUSTABLE COLOR EASTMAN KODAK COMPANY (US) 2010-02-03 EP disclosed
WO-2008150392-A1 LAMP WITH ADJUSTABLE COLOR EASTMAN KODAK COMPANY (US) 2008-12-11 WO disclosed
EP-1388894-A2 OLED apparatus including a series of OLED devices EASTMAN KODAK COMPANY (US) 2004-02-11 EP disclosed
EP-1344652-A2 Transfer of organic material from a donor to form a layer in an oled device EASTMAN KODAK COMPANY (US) 2003-09-17 EP disclosed