SCHEMBL5494929

SCHEMBL5494929

Cc1ccc(/C=C/c2ccc(N(c3ccc(C)cc3)c3ccc(C)cc3)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 4/20 0.56
RELA Q04206 2/20 0.52
ALOX5 P09917 1/20 0.48
PTGS1 P23219 1/20 0.48
PTGS2 P35354 1/20 0.48
CA1 P00915 1/20 0.46
ALDH1A1 P00352 1/20 0.46
TSHR P16473 1/20 0.46
APP P05067 3/20 0.45
MEN1 O00255 3/20 0.45
RAB9A P51151 3/20 0.45
KMT2A Q03164 3/20 0.45
APOBEC3A P31941 2/20 0.45
APOBEC3G Q9HC16 2/20 0.45
NPC1 O15118 2/20 0.44
GAA P10253 1/20 0.44
GFER P55789 1/20 0.44
CYP2A6 P11509 1/20 0.44
TUBB4A P04350 1/20 0.44
TUBB P07437 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5953353 1.00 NFE2L2 (0.56) NFE2L2RELAALOX5PTGS1PTGS2
SCHEMBL5937913 1.00 NFE2L2 (0.56) NFE2L2RELAALOX5PTGS1PTGS2
SCHEMBL5937944 1.00 NFE2L2 (0.56) NFE2L2RELAALOX5PTGS1PTGS2
SCHEMBL5492449 1.00 NFE2L2 (0.56) NFE2L2RELAALOX5PTGS1PTGS2
SCHEMBL16489726 1.00 NFE2L2 (0.56) NFE2L2RELAALOX5PTGS1PTGS2
SCHEMBL3629423 1.00 NFE2L2 (0.56) NFE2L2RELAALOX5PTGS1PTGS2
SCHEMBL10015739 1.00 NFE2L2 (0.56) NFE2L2RELAALOX5PTGS1PTGS2
SCHEMBL75905 1.00 NFE2L2 (0.56) NFE2L2RELAALOX5PTGS1PTGS2
SCHEMBL20663990 1.00 NFE2L2 (0.56) NFE2L2RELAALOX5PTGS1PTGS2
SCHEMBL75906 1.00 NFE2L2 (0.56) NFE2L2RELAALOX5PTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9791791-B2 Electrophotographic photoreceptor, electrophotographic cartridge, image forming apparatus, and charge transport substance MITSUBISHI CHEMICAL CORPORATION (JP) 2017-10-17 US disclosed
US-20160320717-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC CARTRIDGE, IMAGE FORMING APPARATUS, AND CHARGE TRANSPORT SUBSTANCE MITSUBISHI CHEMICAL CORPORATION (JP) 2016-11-03 US disclosed
EP-1989595-B1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, PRODUCTION METHOD THEREOF, IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS USING PHOTOCONDUCTOR, AND PROCESS CARTRIDGE RICOH CO LTD (JP) 2013-08-14 EP disclosed
US-7662485-B2 White organic light-emitting devices with improved performance EASTMAN KODAK COMPANY (US) 2010-02-16 US disclosed
US-7662485-B2 White organic light-emitting devices with improved performance EASTMAN KODAK COMPANY (US) 2010-02-16 US disclosed
US-7276627-B2 One pot sequential reactions and novel products produced thereby IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2007-10-02 US disclosed
US-20070134512-A1 Electroluminescent device containing an anthracene derivative EASTMAN KODAK COMPANY 2007-06-14 US disclosed
US-20070134512-A1 Electroluminescent device containing an anthracene derivative EASTMAN KODAK COMPANY 2007-06-14 US disclosed
US-7201976-B2 Organic electroluminescence material and electroluminescence device using the same SAMSUNG SDI CO., LTD. (KR) 2007-04-10 US disclosed
US-7201976-B2 Organic electroluminescence material and electroluminescence device using the same SAMSUNG SDI CO., LTD. (KR) 2007-04-10 US disclosed
US-20060224017-A1 One pot sequential reactions and novel products produced thereby IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2006-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060224017-A1 One pot sequential reactions and novel products produced thereby PNMT, CYP1A1, TERT NFE2L2 446/4885RELA 1503/4885ALOX5 3278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.