Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3636493 | 0.89 | MAOB (0.33) | HPGDALDH1A1LMNAMAOAMAOB | |
| SCHEMBL3634394 | 0.84 | KCNH2 (0.35) | KCNH2 | |
| SCHEMBL3633217 | 0.82 | KCNH2 (0.35) | KCNH2 | |
| SCHEMBL3634497 | 0.82 | KCNH2 (0.34) | HPGDKCNH2 | |
| SCHEMBL3629842 | 0.82 | GRM2 (0.35) | GRM2MAOAMAOBKCNH2 | |
| SCHEMBL3629666 | 0.80 | KCNH2 (0.34) | HPGDGRM2KCNH2 | |
| SCHEMBL1224025 | 0.80 | KCNH2 (0.34) | HPGDGRM2KCNH2 | |
| SCHEMBL3633671 | 0.80 | MAOA (0.37) | GRM2ALDH1A1MEN1KMT2AMAOA | |
| SCHEMBL1224166 | 0.79 | KCNH2 (0.35) | GRM2ALDH1A1LMNAKCNH2 | |
| SCHEMBL1224167 | 0.79 | KCNH2 (0.35) | GRM2ALDH1A1LMNAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2144910-A2 | OXAZOLIDINONE ANTIBIOTICS | Actelion Pharmaceuticals Ltd. (CH) | 2010-01-20 | — | — | EP | claimed |
| WO-2008126034-A2 | OXAZOLIDINONE ANTIBIOTICS | ACTELION PHARMACEUTICALS LTD (CH) | 2008-10-23 | — | — | WO | claimed |
| EP-2144910-A2 | OXAZOLIDINONE ANTIBIOTICS | Actelion Pharmaceuticals Ltd. (CH) | 2010-01-20 | — | — | EP | disclosed |
| WO-2008126034-A2 | OXAZOLIDINONE ANTIBIOTICS | ACTELION PHARMACEUTICALS LTD (CH) | 2008-10-23 | — | — | WO | disclosed |