Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.31 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30609086 | 0.69 | NOTUM (0.40) | MEN1LMNAKMT2AKDM4EPABPC1 | |
| SCHEMBL13113610 | 0.69 | NOTUM (0.40) | MEN1LMNAKMT2AKDM4EPABPC1 | |
| SCHEMBL4774337 | 0.66 | NOTUM (0.50) | TDP1KDM4EALDH1A1POLBL3MBTL1 | |
| SCHEMBL734868 | 0.64 | PARP1 (0.53) | MEN1LMNAKMT2ATDP1THRB | |
| SCHEMBL29385220 | 0.64 | PARP1 (0.53) | MEN1LMNAKMT2ATDP1THRB | |
| SCHEMBL432800 | 0.64 | HTR1A (0.41) | ALDH1A1TRIM24TRIM33 | |
| SCHEMBL10563082 | 0.64 | RXFP1 (0.45) | MEN1LMNAKMT2ATDP1THRB | |
| SCHEMBL1012582 | 0.63 | KDM4E (0.61) | MEN1LMNAKMT2ATDP1THRB | |
| SCHEMBL161792 | 0.63 | GSK3B (0.54) | MEN1LMNAKMT2ATDP1THRB | |
| SCHEMBL4992978 | 0.63 | MEN1 (0.44) | MEN1LMNAKMT2ATDP1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010149309-A2 | CYCLOALKYLAMIDOBENZOXA(THIA)ZOLES | BAYER CROPSCIENCE AG (DE) | 2010-12-29 | — | — | WO | disclosed |
| WO-2010149283-A2 | PHENYLOXY(THIO)PHENYLAMIDOBENZOXA(THIA)ZOLES | BAYER CROPSCIENCE AG (DE) | 2010-12-29 | — | — | WO | disclosed |