Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4167475 | 0.96 | TSHR (0.48) | TSHRTHRBALDH1A1TP53TDP1 | |
| SCHEMBL6061683 | 0.94 | TSHR (0.43) | TSHRTHRBALDH1A1TP53TDP1 | |
| SCHEMBL2896887 | 0.90 | TSHR (0.43) | TSHRTHRBALDH1A1TP53TDP1 | |
| Trimethylammonium SCHEMBL8027821 | 0.90 | TSHR (0.43) | TSHRTHRBALDH1A1TP53TDP1 | |
| SCHEMBL29250785 | 0.90 | TSHR (0.43) | TSHRTHRBALDH1A1TP53TDP1 | |
| SCHEMBL28200633 | 0.86 | THRB (0.40) | TSHRTHRBALDH1A1PPARDCA12 | |
| SCHEMBL27728666 | 0.84 | TSHR (0.38) | TSHRTHRBALDH1A1PPARD | |
| SCHEMBL29270400 | 0.83 | TSHR (0.36) | TSHRTHRBALDH1A1 | |
| SCHEMBL27836992 | 0.83 | THRB (0.38) | TSHRTHRBALDH1A1CA12CA1 | |
| SCHEMBL418514 | 0.82 | ALDH1A1 (0.50) | TSHRTHRBALDH1A1TDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2146679-B1 | DENTAL COMPOSITIONS FOR COATING RESTORATIONS AND TOOTH SURFACES | DENTSPLY INT INC (US) | 2016-01-06 | — | — | EP | disclosed |
| EP-2146679-A2 | DENTAL COMPOSITIONS FOR COATING RESTORATIONS AND TOOTH SURFACES | Dentsply International Inc. (US) | 2010-01-27 | — | — | EP | disclosed |
| WO-2008140800-A2 | DENTAL COMPOSITIONS FOR COATING RESTORATIONS AND TOOTH SURFACES | DENTSPLY INTERNATIONAL INC. (US) | 2008-11-20 | — | — | WO | disclosed |
| US-7193226-B2 | Scratch resistant moisture-protecting parylene layers | AGFA-GEVAERT (BE) | 2007-03-20 | — | — | US | disclosed |
| EP-1541333-A1 | Scratch resistant moisture-protecting parylene layers | Agfa-Gevaert (BE) | 2005-06-15 | — | — | EP | disclosed |
| US-20050067584-A1 | Scratch resistant moisture-protecting parylene layers | AGFA NV (BE) | 2005-03-31 | — | — | US | disclosed |