Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 6/20 | 0.43 |
| ▸ | TP53 | P04637 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3623767 | 0.85 | TSHR (0.44) | MAPTHTTOPRK1LMNATP53 | |
| SCHEMBL3633776 | 0.77 | LMNA (0.48) | MAPTLMNATP53TSHRSMN1; SMN2 | |
| SCHEMBL26327902 | 0.71 | TSHR (0.55) | MAPTHTTOPRK1LMNATP53 | |
| SCHEMBL27791609 | 0.71 | MAPT (0.42) | MAPTHTTOPRK1LMNATP53 | |
| SCHEMBL9926131 | 0.70 | USP2 (0.65) | MAPTHTTLMNATP53TSHR | |
| SCHEMBL9926061 | 0.70 | SMN1; SMN2 (0.47) | MAPTHTTOPRK1LMNATP53 | |
| SCHEMBL1735650 | 0.69 | MAPT (0.50) | MAPTHTTLMNATP53TSHR | |
| SCHEMBL1735652 | 0.69 | MAPT (0.50) | MAPTHTTLMNATP53TSHR | |
| SCHEMBL3646495 | 0.69 | LMNA (0.50) | MAPTHTTLMNATP53TSHR | |
| SCHEMBL3651857 | 0.69 | LMNA (0.51) | MAPTHTTLMNATP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142533-A1 | IMIDAZOLIDINONE DERIVATIVES | F. Hoffmann-Roche AG (CH) | 2010-01-13 | — | — | EP | disclosed |
| WO-2008119657-A1 | IMIDAZOLIDINONE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-10-09 | — | — | WO | disclosed |