Ethylene Glycol

Ethylene Glycol

SCHEMBL3631014

O=C(O)C(C(C(=O)O)(N1C(=O)CCC1=O)S(=O)(=O)O)S(=O)(=O)O.OCCO

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL949639 0.94
SCHEMBL1352998 0.83
SCHEMBL29981082 0.81
SCHEMBL28546521 0.75 KMT2A (0.30)
SCHEMBL15876545 0.75
SCHEMBL471957 0.70 PTGER4 (0.31)
Ethylene Glycol SCHEMBL243462 0.69
Ethylene Glycol SCHEMBL4563857 0.69
Ethylene Glycol SCHEMBL31079756 0.68 ALDH1A1 (0.35)
SCHEMBL454927 0.66 ALDH1A1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1447081-B1 Sugar-modified liposome and products comprising the liposome NAT INST OF ADVANCED IND SCIEN (JP) 2010-02-10 EP disclosed
US-20070286896-A1 Therapeutic or Diagnostic Drug for Inflammatory Disease Comprising Targeting Liposome NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY 2007-12-13 US disclosed
US-20070160657-A1 Targeting and intestinal-absorption controlled liposome having sugar chain and therapeutic drug for cancer and diagnostic drug containing the liposome NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE (JP) 2007-07-12 US disclosed
US-20060193906-A1 Sugar-modified liposome and products comprising the liposome NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY 2006-08-31 US disclosed
US-7070801-B2 Sugar-modified liposome and products comprising the liposome NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2006-07-04 US disclosed
EP-1655038-A1 TARGET-DIRECTED AND ENTERIC ABSORPTION-CONTROLLED LIPOSOME HAVING SUGAR CHAIN AND CANCER REMEDY AND DIAGNOSTIC CONTAINING THE SAME National Institute of Advanced Industrial Science and Technology (JP) 2006-05-10 EP disclosed
EP-1655022-A1 REMEDY OR DIAGNOSTIC FOR INFLAMMATORY DISEASE CONTAINING TARGET-DIRECTING LIPOSOME National Institute of Advanced Industrial Science and Technology (JP) 2006-05-10 EP disclosed
EP-1447081-A1 Sugar-modified liposome and products comprising the liposome National Institue of Advanced Industrial Science and Technology (JP) 2004-08-18 EP disclosed
US-20030143267-A1 Sugar-modified liposome and products comprising the liposome NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL 2003-07-31 US disclosed